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The effect of magnesium supplementation on blood pressure in individuals with insulin resistance, prediabetes, or noncommunicable chronic diseases: a meta-analysis of randomized controlled trials
blood pressure cardiovascular diseases insulin resistance
2018/11/16
Background: To our knowledge, the effect of magnesium supplementation on blood pressure (BP) in individuals with preclinical or noncommunicable diseases has not been previously investigated in a meta-...
Fructose replacement of glucose or sucrose in food or beverages lowers postprandial glucose and insulin without raising triglycerides: a systematic review and meta-analysis
sugar replacement, fructose, glucose, sucrose, insulin, triglycerides, diabetes, body weight
2018/11/15
Background: Conflicting evidence exists on the effects of fructose consumption in people with type 1 and type 2 diabetes mellitus. No systematic review has addressed the effect of isoenergetic fructos...
Effect of fructose consumption on insulin sensitivity in nondiabetic subjects: a systematic review and meta-analysis of diet-intervention trials
fructose glucose clamp glucose disposal insulin insulin resistance meta-analysis
2018/12/19
Background: High fructose consumption has been suggested to contribute to several features of metabolic syndrome including insulin resistance, but to our knowledge, no previous meta-analyses have inve...
Do ω-3 PUFAs affect insulin resistance in a sex-specific manner? A systematic review and meta-analysis of randomized controlled trials
adults diabetes omega-3 PUFAs DHA EPA insulin resistance insulin sensitivity
2018/12/19
Background: Evidence has suggested that omega-3 (n–3) polyunsaturated fatty acids (PUFAs) improve obesity-induced insulin resistance (IR); however, results from human intervention trials have been equ...
Gut permeability is related to body weight, fatty liver disease, and insulin resistance in obese individuals undergoing weight reduction
obesity liver steatosis insulin resistance intestinal permeability gut barrier
2018/11/12
Background: Obesity and associated metabolic disorders are related to impairments of the intestinal barrier.
Objective: We examined lactulose:mannitol (Lac:Man) permeability in obese individuals with...
Effect of vitamin D replacement on indexes of insulin resistance in overweight elderly individuals: a randomized controlled trial
HOMA insulin resistance prediabetes IOM RDA high-dose vitamin D
2018/12/3
Background: It is unclear whether and at what dose vitamin D supplementation affects insulin resistance (IR).
Insulin sensitivity is a Rubik’s Cube
Insulin sensitivity complex metabolic exercise diet
2018/11/30
Insulin sensitivity is determined by complex metabolic interactions dictated by a multitude of inputs that include inherited genetic and epigenetic determinants as well as many varying modifiers such ...
Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial
insulin sensitivity mitochondrial capacity obesity polyphenols resveratrol
2018/12/3
Background: The obese insulin-resistant state is characterized by impairments in lipid metabolism. We previously showed that 3-d supplementation of combined epigallocatechin-3-gallate and resveratrol ...
Adipose tissue α-linolenic acid is inversely associated with insulin resistance in adults
adiposity biomarker insulin resistance n–3 fatty acids waist circumference
2018/11/29
Background: There is emerging evidence of the beneficial effects of n–3 (ω-3) fatty acids (FAs) on cardiometabolic risk factors. Nevertheless, not much is known about the association between adipose t...
The Effects of Chromium on Skeletal Muscle Membrane/Cytoskeletal Parameters and Insulin Sensitivity
Cholesterol Actin Skeletal muscle
2015/5/22
A recent review of randomized controlled trials found that trivalent chromium (Cr3+) supplementation significantly improved glycemia among patients with diabetes, consistent with a long-standing appre...