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Responses to Neonicotinoids of Chicken α7 Nicotinic Acetylcholine Receptors：Effects of Mutations of Isoleucine 191 in Loop F to Aromatic Residues
imidacloprid neonicotinoid desnitro-imidacloprid nicotinic acetylcholine receptor chicken α7 subunit, loop F
2009/3/7
The effects on the responses to neonicotinoids and related nicotinic agonists of three site-directed mutations (I191W, I191F and I191Y) in loop F of the acetylcholine-binding site were studied using...
Neonicotinoids and Derivatives：Effects in Mammalian Cells and Mice
analgesia extracellular signal-regulated kinase cascade neonicotinoids nicotinic receptors
2009/3/6
Neonicotinoids are the only major new class of insecticides introduced in the past three decades. They act as selective agonists at the insect nicotinic acetylcholine receptor and are therefore high...
Preparation of Alkylene-Tethered Acyclic Divalent Neonicotinoids and Their Insecticidal and Neuroblocking Activities for American Cockroach（Periplaneta americana L）
alkylene-tethered divalent molecule nicotinic acetylcholine receptor neuroblocking activity American cockroach
2009/3/6
C4-C8 and C12-alkylene- or 1,4-xylylene-tethered bis[1-(6-chloro-3-pyridylmethyl)]- or bis[1-(2-chloro-5-thiazolylmethyl)]-2-nitroimino-3-guanidines were prepared. The insecticidal potency against...
Molecular Mechanism of Selective Toxicity of Neonicotinoids
neonicotinoid imidacloprid nicotinic acetylcholine receptor selective toxicity voltage-clamp electrophysiology
2009/3/5
Actions of neonicotinoids on wild-type and mutant α7 nicotinic receptors were investigated using voltage-clamp electrophysiology to elucidate the mechanism underlying the selectivity of neonicotinoi...
Insecticidal and Neuroblocking Activities in the American Cockroach（Periplaneta americana L.）of Mannich Bases of Nitromethylene Imidazolidine Neonicotinoids
proinsecticide nitromethylene insecticide Mannich adduct neuroblocking potency American cockroach
2009/3/5
The insecticidal and neuroblocking activities of Mannich bases prepared from chloronicotinyl- and chlorothiazolylmethyl-nitromethylenimidazolidines, known potent insecticides, were measured in Ameri...
Actions of imidacloprid, clothianidin and related neonicotinoids on nicotinic acetylcholine receptors of American cockroach neurons and their relationships with insecticidal potency
imidacloprid clothianidin neonicotinoids nicotinic acetylcholine receptors
2009/3/5
The actions of neonicotinoid insecticides on nicotinic acetylcholine receptors (nAChRs) in the terminal abdominal ganglion neurons of the American cockroach were investigated using whole-cell patch-...
Potentiating and blocking actions of neonicotinoids on the response to acetylcholine of the neuronal α4β2 nicotinic acetylcholine receptor
ion channels imidacloprid clothianidin thiacloprid neonicotinoids
2009/3/5
Effects of imidacloprid, clothianidin, thiacloprid and related compounds on the acetylcholine (ACh)-induced response of the recombinant, expressed chicken α4β2 nicotinic acetylcholine receptor (nACh...