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Cytotoxic Activity and Apoptosis Induction of Hypericum scabrum L.
Traditional Medicine Caspase-3 Apoptosis Annexin V Protein
2015/11/9
Background: One of the acquired biological hallmarks of tumor multistep development is the resistance of cancer cells to apoptosis; therefore, induction of apoptosis is an important therapeutic approa...
Developing and Implementing Guidelines for the Safe Handling of Cytotoxic Drugs and Related Waste: The Queensland Experience
Developing and Implementing Guidelines the Safe Handling Cytotoxic Drugs Related Waste The Queensland Experience
2015/3/9
A greater understanding of the nature of cancer and the role of cytotoxic drugs in treating malignant and non-malignant disease has led to an increase use of chemotherapy in a variety of clinical and ...
Cytotoxic Properties of Some Medicinal Plant Extracts from Mazandaran,Iran
Cytotoxins Medicinal Plant Iran
2015/10/9
Background: It was shown that plants derived agents are being used for treatment of cancer. In this study, crude ethanolic extract of Consolida orientalis L., Ferula assa-foetida L., Coronilla varia L...
Differences in Vaginal Lactobacilli Composition of Iranian Healthy and Bacterial Vaginosis Infected Women: A Comparative Analysis of Their Cytotoxic Effects with Commercial Vaginal Probiotics
Vagina Bacterial Vaginosis Women T-Lymphocytes Cytotoxic Probiotic Iran
2015/9/29
Background: Vaginal flora of healthy women is dominated by Lactobacillus species which can prevent bacterial vaginosis.
In vitro Cytotoxic and Antimicrobial Activity of Essential Oil From Satureja Intermedia
Satureja Gas Chromatography-Mass Spectrometry Thymol
2015/9/29
Background: Many members of the genus Satureja have aromatic and medicinal characteristics.
Objectives: The purpose of the present work was to determine cytotoxic activity of the essential oil of S....
The Cytotoxic Activity of Various Herbals against Different Tumor Cells:An in Vitro Study
Salvia santolinifolia Salvia eremophil Salvia macrosiphon Salvia reuterana
2015/9/21
ackground: Medicinal plants have been investigated for possible anti-cancer effects. The aim of the present study was to examine the cytotoxic activity of several medicinal native plants on different ...
Cytotoxic effects of caffeic acid phenethyl ester (CAPE) on the human multiple myeloma cell line
Caffeic acid phenethyl ester (CAPE) multiple myeloma cytotoxicity IL-6
2010/1/11
Aim: Caffeic acid phenethyl ester (CAPE) has cytotoxic, apoptotic, and antiproliferative effects on various tumor cells, and is the most active component of propolis. This study aimed to examine the i...
Involvement of metabolic reactive intermediate Cr (IV) in Chromium (VI) cytotoxic effects
Chromium Hepatocytes Reactive intermediate
2009/12/28
Addition of Cr VI (dichromate) to isolated rat hepatocytes results in rapid glutathione oxidation, reactive oxygen species (ROS) formation, lipid peroxidation, decreased mitochondrial membrane potenti...
Proliferation of cytotoxic and activated T cells during acute Epstein-Barr virus induced Infectious Mononucleosis
Epstien-Barr virus flow cytometry T lymphocytes
2009/12/24
The immune responses that develop following Epstien-Barr Virus (EBV) infection are complex and involve both humoral and to a greater extent cell-mediated immune mechanisms. To evaluate the immune resp...
Antibacterial,antifungal and cytotoxic activities of 3,5-diacetyltambulin isolated from Amorphophallus campanulatus Blume ex.Decne
Flavonoid Gram-positive Gram-negative MIC Cytotoxicity
2009/12/18
Background and purpose of the study: Amorphophallus campanulatus is widely distributed in Bangladesh, India, and Africa and the tuberous roots of the plant has many traditional uses and is an importan...
The in Vitro Effect of Plasmodium berghei Antigen Lysate on Natural Killer (NK) Cell Cytotoxic Activity
Natural killer (NK) cell cytotoxicity Plasmodium berghei
2009/7/2
Plasmodium berghei is the rodent equivalent of Plasmodium falciparum which causes cerebral malaria in humans. However, P. berghei does not cause cerebral malaria in BALB/c mice, instead it leads to pa...
Arsenic Trioxide Has Additive Cytotoxic Effects on MCF-7 Breast Cancer Cell Line With Taxanes
breast cancer MCF-7 arsenic trioxide docetaxel paclitaxel
2009/6/25
Breast cancer is the most prevalent cancer in women and an important cause of both morbidity and mortality. Although long-term disease-free survival is offered to women with early stage disease by cur...
Evaluation of Cytotoxic Potential of Newly Synthesized Antiviral Aminopyrazoloquinoline Derivatives
aminopyrazoloquinoline apoptosis DNA damage MCF-7 MDA-MB-231
2009/4/20
In the present study, we screened newly synthesized antiviral aminopyrazoloquinoline derivatives for cytotoxic potential in human normal and breast cancer cell lines using apoptosis as biomarker....
Quantitative Correlation Between Testicular Stem Cell Survival, Sperm Production, and Fertility in the Mouse After Treatment With Different Cytotoxic Agents
stem cells sperm production fertility radiation Adriamycin
2009/2/19
Treatment of mice with high doses of radiation or certain cytotoxic drugs results in killing of spermatogonial stem cells, a prolonged period of reduced sperm production, and infertility. In this ...
Quantitative Correlation Between Testicular Stem Cell Survival, Sperm Production, and Fertility in the Mouse After Treatment With Different Cytotoxic Agents
stem cells sperm production fertility radiation Adriamycin
2009/2/19
Treatment of mice with high doses of radiation or certain cytotoxic drugs results in killing of spermatogonial stem cells, a prolonged period of reduced sperm production, and infertility. In this ...