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评估支气管肺泡灌洗液（BALF）应用结核分枝杆菌环介导等温扩展技术（TB-LAMP）对菌阴肺结核诊断中的应用价值。方法收集某院2017年12月— 2018年11月临床确诊为菌阴肺结核（3次痰涂片阴性且痰培养阴性）的254例患者的资料，所有患者行支气管检查取支气管镜刷检物或BALF标本，同时分为LAMP组（进行涂片）抗酸染色，罗氏培养，TB-LAMP检测）的GeneXpert组（进行涂片抗酸染色，罗...
HIV/AIDS-TB患者抗结核药物治疗强化期红细胞系的变化
艾滋病, 肺结核 抗结核药物治疗 红细胞系
2020/5/29
分析接受抗逆转录病毒治疗（ART）及不同ART方案联合抗结核药物治疗的人类免疫缺陷病毒/艾滋病合并结核分枝杆菌感染（HIV/AIDS-TB）患者在强化期内血液学红细胞系的变化情况。方法 选取2014-2017年某传染病专科医院确诊为HIV/AIDS-TB的患者，分为在ART基础上接受抗结核药物联合治疗组（A组），抗结核药物治疗8周内开始ART联合治疗组（B组），抗结核药物治疗8周后开始ART治疗组...
四川大学华西基础医学与法医学院医学微生物学（1）课件 Diph+TB。
Addressing TB Risk Factors May Be Fruitful Approach to Mitigating Disease（图）
TB Risk Factors Fruitful Approach Mitigating Disease
2017/9/5
In the era of multi-drug resistant strains of tuberculosis (TB), it is important to identify other ways to mitigate and prevent disease. According to the World Health Organization (WHO), an estimated ...
A distinctive genetic “signature” offers new hope for developing a rapid, affordable diagnostic test for the hundreds of thousands of children infected with tuberculosis each year.
The Prevalence of Tb in HIV Patients and Risk Factor With Frequent Referral (Iran, 2009-10)
HIV Tuberculosis Prevalence Coinfection
2015/9/29
Background: HIV infection significantly increases the risk of tuberculosis and this disease is one of the most common opportunistic infections in HIV Patients.
HIV/TB患者抗结核治疗强化期发生肝损伤的危险因素
获得性免疫缺陷综合征 危险因素 抗结核治疗 肝损伤
2014/2/21
探讨HIV/TB患者在标化抗结核治疗强化期，肝损伤的发生情况及其影响因素。方法 对采用标化抗结核治疗的400例HIV/TB患者，观察强化期肝损伤发生率。选择15个可能对肝损伤产生影响的临床指标行Logistic回归分析。结果 本组HIV/TB患者抗结核肝损伤的发生率为36.25%。单因素分析显示：体重减轻、既往肝损伤史、静脉途径用药、CD4+T淋巴细胞计数、白蛋白定量、合并HBV感染以及治疗后嗜酸...
胸水中TB-Ab TB-DNA联合检测对结核性胸膜炎的诊断价
胸水
2011/9/28
结核性胸膜炎是一种常见病、多发病，尤其是老年人，近年的发病率更有显著上升趋势[1]。由于该病在临床上缺乏特异性表现，用细菌学方法检测敏感性不高，胸膜活检又存在一定的创伤性和危险性，所以给初诊患者的确诊带来了一定难度[2]。现对结核性胸膜炎患者的胸水进行TB-Ab和TB-DNA检测及联合检测，并与传统的胸水涂片抗酸染色、罗氏培养检测结果比较，以探讨其在结核性胸膜炎诊断中的应用价值。
Expression and Purification of Recombinant Mycobacterium Tuberculosis (TB) Antigens, ESAT-6, CFP-10 and ESAT- 6/CFP-10 and Their Diagnosis Potential for Detection of TB Patients
Mycobacterium tuberculosis ELISPOT CFP-10 ESAT-6 Tuberculosis Diagnosis
2015/9/23
Background: One of the most widely used methods to detect tuberculosis (TB) infection is the tuberculin skin test (TST). The completion of Mycobacterium tuberculosis (M. tuberculosis) genome sequence ...
近年来，我国结核病的发病率有上升趋势，临床上经常会遇到一些症状不典型的结核病和肺外结核病，而目前可用于诊断结核病的方法有限，同时又缺乏快速敏感的实验室技术，为结核病的早期诊断与治疗带来困难。ELISPOT（enzyme-linked immunospot assay, 酶联免疫斑点法）技术是一种新型的免疫酶技术，它是从单细胞水平检测分泌抗体细胞或分泌细胞因子细胞[1]。由ELISPOT发展来的T ...
Genetic signature in TB patients sheds light on disease
Genetic signature TB patients disease
2010/8/26
Medical Research Council (MRC) scientists have uncovered a ‘genetic signature’ in the blood of patients with active tuberculosis (TB). This discovery could not only serve as the basis of future diagno...
A specialist in public health at the University of Sheffield is supporting calls for global action on Tuberculosis (TB), in support of World TB Day which takes place this week (24 March 2010). Dr Andr...