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Synergistic effects of Isatis tinctoria L. and tacrolimus in the prevention of acute heart rejection in mice
satis tinctoria L mice
2013/6/26
Although immunosuppressive treatments are available for acute cardiac rejection no viable treatment exists for long-term cardiac graft failure. Moreover, the extended use of calcineurin inhibitor immu...
The Clinical Efficacy of Low-Dose Tacrolimus Combined with Tripterygium to Treat the Steroid-Resistant Nephrotic Syndrome
Steroid-Resistant Nephrotic Syndrome Tacrolimus Tripterygium Treatment Outcome
2013/1/31
Objective: To observe the clinical efficacy and safety of low dose tacrolimus (TAC) combined with tripterygium (TW) in treatment of steroid resistant nephritic syndrome (SRNS). Method: The patients, w...
How Safe Is Conversion from Tacrolimus to Its Generic Drug?—A Single Center Experience
Kidney Pharmacoeconomics Tacrolimus Transplantation
2013/1/31
Background: Generically produced cyclosporine has long been approved in the treatment of organ transplant recipients and several publications have dealt with its use. For tacrolimus, however, very few...
Rapamycin or tacrolimus alone fails to resist cardiac allograft accelerated rejection mediated by alloreactive CD4(+) memory T cells in mice
Rapamycin tacrolimus rejection
2013/6/26
Donor-reactive memory T (Tm) cells undermine transplanted organs more readily than naive T cells. Rapamycin (RAPA) and tacrolimus (FK-506) are current mainstay immunosuppressants used for preventing a...
Biochemical evaluation of glycemic levels of long-term tacrolimus therapy in rats
Tacrolimus [adverse effects] Glycemic index Diabetes mellitus Rats
2009/10/19
One of the more serious complications following transplantation is the development of post-transplantation diabetes mellitus (PTDM), which has a major impact on the quality of life, with effects rangi...
Suplatast/Tacrolimus Combination Therapy for Refractory Facial Erythema in Adult Patients with Atopic Dermatitis—A Meta-Analysis Study—
atopic dermatitis erythema meta-analysis suplatast tacrolimus
2010/11/18
Background: Combination of suplatast tosilate with tacrolimus ointment was reported to reduce the dose of tacrolimus ointment with maintained treatment efficacy for refractory facial erythema in atopi...