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Background: sFasL is the soluble form of FasL inducing apoptosis by binding to Fas. Fas/sFasL could be the most important mechanisms in inflammatory conditions such as asthma by controlling inflammato...
Reduction of Eosinophils in Small Airways by Inhaled Steroids is Insufficient in Patients with Adult Asthma
bronchial asthma eosinophil inhaled corticosteroid small airways treatment
2010/11/19
Background: Recent reports suggest that small airway as well as large airway involvement in asthma is important. We investigate the therapeutic effects of a meter-dose inhaler of chrolofluorocarbon-be...
Signal transducers and activators of transcription 6 (Stat6) variants in childhood and adult asthma
atopy dinucleotide repeat polymorphism interleukin-13 interleukin-4 signal transducers and activators of transcription 6 (Stat6)
2010/11/22
Background: Signal transducers and activators of transcription 6 (Stat6) is a key transcription factor involved in interleukin (IL)-4 and IL-13-mediated biological responses. Recently, we reported the...
Childhood Onset Adult Asthma: A Comparison of Asthma Development with Exposure to High and Reduced Levels of Air Pollution
adult asthma ambient air pollution infancy onset asthma lung function tests non-specific bronchial hyperreactivity
2010/11/22
The dramatic increase of infancy onset asthmatic born after 1960 coincided with the increases in levels of air pollution. The infancy onset adult asthmatics born in 1960s were more hypersensitive to n...