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Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
Hydroxychloroquine less toxic derivative chloroquine effective inhibiting SARS-CoV-2 infection vitro
2020/6/12
The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2/2019-nCoV) poses a serious threat to global public health and local econom...
Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
Remdesivir chloroquine effectively inhibit novel coronavirus (2019-nCoV) vitro
2020/6/12
In December 2019, a novel pneumonia caused by a previously unknown pathogen emerged in Wuhan, a city of 11 million people in central China. The initial cases were linked to exposures in a seafood mark...
Antiplasmodial effects of Brucea javanica (L.) Merr. and Eurycoma longifolia Jack extracts and their combination with chloroquine and quinine on Plasmodium falciparum in culture
Plasmodium falciparum Brucea javanica (L.) Merr
2010/12/10
Fruits of Brucea javanica (L.) Merr. (“Ratchadad” in Thai) and roots of Eurycoma longifolia Jack (“Plalaipeag” in Thai) are used as traditional medicines for the treatment of malarial fever. Ethanol, ...
THE EFFECT OF CHLOROQUINE ON THE INFECTIVITY OF RODENT MALARIA PARASITES TO ANOPHELES STEPHENSI
Anopheles stephens Chloroquine P.y. nigeriensis
2010/1/4
There was a statistically significant difference in the number of oocysts, developed in Anopheles stephensi which had fed on mice infected with chloroquine resistant strains (NY 151./2B and. P.y. nige...
Variation of the Chloroquine Resistance Transporter (Crt) Gene in Chloroquine-Resistant and Chloroquine-Sensitive Plasmodium berghei
Chloroquine resistance Plasmodium berghei Crt gene
2009/12/11
Background: The emergence and spread of chloroquine resistant Plasmodium falciparum in the world stimulated some investigators to consider different aspects of chloroquine resistance in human and rode...
Variation of the Chloroquine Resistance Transporter (Crt) Gene in Chloroquine-Resistant and Chloroquine-Sensitive Plasmodium berghei
Chloroquine resistance Plasmodium berghei Crt gene
2009/12/11
Background: The emergence and spread of chloroquine resistant Plasmodium falciparum in the world stimulated some investigators to consider different aspects of chloroquine resistance in human and rode...
Chloroquine resistance molecular markers in Falciparum malaria in Edo state
Prevalence Pfcrt K76T Pfmdr
2010/12/10
The epidemiology survey of Pfcrt and Pfmdr 1 mutant genes in malaria infection in Edo State was carried out between June 2005 and May 2006. Five hundred and sixty one (561) subjects with a history of ...
Effect of chloroquine on the formation of tight junctions in cultured immature rat Sertoli cells
Sertoli cells TEA chloroquine
2009/2/16
Adjoining immature Sertoli cells in the seminiferous epithelium form a tight junctional complex leading to the development of the blood-testis barrier. Protease and antiprotease activities have been...
Evaluation of Sensitivity of Plasmodium vivax to Chloroquine
Malaria Plasmodium vivax Chloroquine Iran
2010/4/19
Background: To monitor the current response of P. vivax to chloroquine in South and Southeast Iran.
Methods: The study was undertaken from August 2004 until August 2005 at the Bandar- Abbas, Iranshah...
IN VIVO EVALUATION OF COMBINATION EFFECTS OF CHLOROQUINE WITH CEPHARANTHIN® OR MINOCYCLINE HYDROCHLORIDE AGAINST BLOOD-INDUCED CHLOROQUINE-RESISTANT PLASMODIUM BERGHEI NK 65 INFECTIONS
Plasmodium berghei NK 65 Cepharanthin minocycline
2010/12/10
The combination effects of chloroquine with Cepharanthin® or minocycline hydrochloride were evaluated against a blood-induced infection with chloroquine-resistant P. berghei NK 65 in ICR mice. The...