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GlycA, a novel proinflammatory glycoprotein biomarker, and high-sensitivity C-reactive protein are inversely associated with sodium intake after controlling for adiposity: the Prevention of Renal and Vascular End-Stage Disease study
C-reactive protein diet GlycA glycoproteins inflammation nuclear magnetic resonance spectroscopy sodium excretion
2018/12/3
Background: The extent to which dietary sodium intake may confer alterations in the inflammatory status is unclear. GlycA is a novel proton nuclear magnetic resonance spectroscopy-measured biomarker o...
GlycA, a novel proinflammatory glycoprotein biomarker, and high-sensitivity C-reactive protein are inversely associated with sodium intake after controlling for adiposity: the Prevention of Renal and Vascular End-Stage Disease study
C-reactive protein diet GlycA glycoproteins inflammation nuclear magnetic resonance spectroscopy sodium excretion
2018/12/13
Background: The extent to which dietary sodium intake may confer alterations in the inflammatory status is unclear. GlycA is a novel proton nuclear magnetic resonance spectroscopy-measured biomarker o...
P-glycoprotein的新功能在肿瘤研究中的进展
P-glycoprotein 多药耐药 增殖 凋亡 迁移 上皮间质转化 血管生成
2015/7/20
肿瘤多药耐药性（multiple drug resistance，MDR）的发生往往伴随着多药耐药基因如MDR1、MRP 1 和BCRP等高表达，其中MDR1 基因编码的P-糖蛋白（P-glycoprotein ，P-gp）是目前公认可以诱发癌细胞发生MDR的重要分子。传统研究认为P-gp主要是作为一个药物泵将化疗药物从细胞内排出从而导致MDR。然而系列研究发现，除了介导MDR以外，P-gp还能够...
Clinical Significance of P-Glycoprotein Immunohistochemistry and Histomorphologic Factors in Patients with Osteosarcoma
Osteosarcoma Prognosis Immunohistochemistry P-glycoprotein
2015/9/18
Background: Osteosarcoma is the most frequent highly malignant bone tumor with a peak incidence in the second decade of life. Although survival rate increased up to 60-70% within the last 10 years, th...
Clinical Significance of P-Glycoprotein Immunohistochemistry and Histomorphologic Factors in Patients with Osteosarcoma
Osteosarcoma Prognosis Immunohistochemistry P-glycoprotein
2015/9/18
Background: Osteosarcoma is the most frequent highly malignant bone tumor with a peak incidence in the second decade of life. Although survival rate increased up to 60-70% within the last 10 years, th...
Glycoprotein IIb/IIIa Inhibitors in Acute Coronary Syndromes: A new Paradigm in Cardiology
Coronary Syndromes Cardiology Glycoprotein
2009/7/2
Acute coronary syndromes, namely, unstable angina and myocardial infarction, remain a major cause of morbidity and mortality (1). The light has been shed on the pathogenesis of these syndromes by rece...
The Effects of Benzo(A) Pyrene Doxorubicin and Paclitaxel on P170 Glycoprotein
benzo(a)pyrene doxorubicin paclitaxel p170 glycoprotein rat
2009/6/29
B(a)P is a mutagenic, carcinogenic and teratogenic substance. Paclitaxel and doxorubicin are antineoplastic drugs widely used in cancer treatment. The purpose of this study is to observe the effects o...
Determination of Polydispersity of a Human Colonic Mucus Glycoprotein Using Rate-Zonal Centrifugation and Laser Light-Scattering
Polydispersity colonic mucins rate-zonal centrifugation light-scattering
2009/6/25
The colonic epithelium is coated by a visco-elastic gel, mucus that lubricates and protects the mucosa from the external environment. Mucus glycoproteins (mucins, MUCs) are major macromolecular compon...
Increased Prevalence of Glycoprotein IIb/IIIa Leu 33 Pro Polymorphism in End Stage Renal Disease Patients on Hemodialysis
hemodialysis fibrinogen receptor polymorphism glycoprotein platelets CVD
2009/4/14
Traditional atherosclerosis risk factors cannot elucidate the increased prevalence of cardiovascular events in end stage renal disease (ESRD) patients on hemodialysis. A previous study has indicated a...
Effect of zinc on hepatoprotectivity of α1-acid glycoprotein
αl-acid glycoprotein zinc hepatoprotection thermal property
2009/4/1
αl-Acid glycoprotein (AGP) prevented primary hepatocytes from undergoing cell death induced by the chemical toxin, bromobenzene at range from 0.1 to 0.2 mg/ml. Addition of zinc (0.2 mM) to medium cont...
Further characterization of a secreted epididymal glycoprotein in mice that binds to sperm tails
Further characterization secreted epididymal glycoprotein mice sperm tails
2009/2/23
Sperm maturation antigen 4 (SMA-4) is a surface component of the mouse sperm tail. Previously, immunofluorescence studies indicated that SMA-4 may be secreted by principal cells of the distal caput ...
Decreased fertility and motility of spermatozoa from rats immunized with a prealbumin epididymal-specific glycoprotein
acidic epididymal glycoprotein spermatozoa rat immunization fertility
2009/2/23
This study investigated the effects on the progressive motility, zona-binding capacity, and fertility of spermatozoa from the cauda epididymidis of adult male rats that were actively immunized again...
Synthesis and secretion of glycoprotein by the epididymal epithelium
Synthesis secretion glycoprotein epididymal epithelium
2009/2/19
The secretory activity of the middle segment of the mouse caput epididymidis was studied using 3H-fucose as a precursor to glycoprotein. Young adult male mice were injected with a concentrated sol...
Cloning and characterization of an androgen-dependent acidic epididymal glycoprotein/CRISP1-like protein from the monkey
Gutknecht J Brew K Spur N. Goodfellow PN. Cloning
2009/2/18
A cDNA encoding an acidic epididymal glycoprotein (AEG)-like, CRISP1 (cysteine-rich secretory protein) protein from the monkey (Macaca mullata) epididymis has been cloned and sequenced. The monkey A...
Mouse testicular sulfated glycoprotein-1：sequence analysis of the common backbone structure of prosaposins
Mouse testicular sulfated glycoprotein-1 common backbone structure prosaposins
2009/2/17
We have generated a cDNA encoding the mouse sulfated glycoprotein-1 (SGP-1) by polymerase chain reaction amplification of a mouse testicular Uni-Zap XR cDNA library with two synthetic oligonucleotid...