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Effects of a single dose of N-Acetyl-5-methoxytryptamine (Melatonin) and resistance exercise on the growth hormone/IGF-1 axis in young males and females
N-Acetyl-5-methoxytryptamine resistance exercise growth hormone/IGF-1 axis young males and females
2015/7/13
Melatonin and resistance exercise alone have been shown to increase the levels of growth hormone (GH). The purpose of this study was to determine the effects of ingestion of a single dose of melatonin...
Urinary Melatonin Levels and Risk of Postmenopausal Breast Cancer in the Women's Health Initiative Observational Study
breast cancer postmenopausal melatonin invasive
2014/11/6
Prior studies have observed a link between night shift work and increased risk of breast cancer. Melatonin, a hormone related to circadian rhythm, has been proposed to lower breast cancer risk by inhi...
Melatonin and Testicular Damage in Busulfan Treated Mice
Melatonin Spermatogenesis Busulfan Mice Testis
2015/10/10
Background:: Advancement in the treatment of various types of cancer has led to greater patient survival. These treatments essentially have toxic effects on different kinds of cells, such as germ cell...
Pinealectomy and Exogenous Melatonin Regulate Anxiety-Like and Depressive-Like Behaviors in Male and Female Wistar Rats
Pinealectomy Melatonin Sex Dependent Anxiety Depression Behavioral Tests
2013/1/30
The main objective of this work was to 1) study the influence of endogenous melatonin (Mel) abolishment via pinealectomy and 2) explore exogenous Mel effect on anxiety-like and depressive-like behavio...
Effects of vitamin A and C and melatonin on 3-nitrotyrosine formation in guinea pig heart under lipopolysaccharide-induced stress
Lipopolysaccharide peroxynitrite 3-nitrotyrosine vitamin A vitamin C melatonin
2010/10/14
Bacterial lipopolysaccharide (LPS) triggers synthesis of nitric oxide (NO) and superoxide (O2.-). O2.- can react with NO to produce the powerful oxidant peroxynitrite (ONOO-). The presence of 3-nitrot...
Evaluation And Comparison Of Serum Melatonin Determination In Normal Individuals And Migraine Patients
Melatonin ELISA kit and Pineal gland
2009/12/24
Background: Migraine is a chronic hereditary and relapsing headache. With regard to the prevalence of this ancient disease and its economic complications in country, in this study , nocturnal serum me...
Melatonin对大鼠肝再灌注损伤的保护作用
Melatonin 大鼠 肝再灌注损伤 保护作用
2009/7/28
目的: 探讨褪黑素对大鼠肝再灌注损伤的影响作用及其机制.方法: 150只健康♂ Wistar大鼠(质量190-210 g，6-7周龄)，随机分为褪黑素处理组(Mel)、酒精溶媒对照组(Alc)和生理盐水对照组(NS). 建立肝缺血再灌注损伤模型，缺血均为60 min，之后每组分别按再灌注后30 min、1、6、12、24 h采集标本. M组(20 mg/kg)于缺血前30 min腹腔注射mela...
Effect of Melatonin on Hepatic Fibrogenesis,Vitamin C and Hydroxyproline Levels in Liver of Ethanol-Fed Rats
Hydroxyproline ascorbic acid alcoholic fibrosis melatonin
2009/6/30
Pineal-gland-derived melatonin (N- Acetyl 5-Methoxytryptamine), which is a known antioxidant hormone, is known to have inhibitory effects on cell growth and proliferation. Ethanol causes increases in...
The Effect of Levonorgestrel and Melatonin Treatments on Plasma Oxidant-Antioxidant System,and Lipid/Lipoprotein Levels in Female Rats
Levonorgestrel melatonin the risk of cardiovascular disease oxidant-antioxidant system lipid-lipoprotein profiles
2009/6/29
This study was carried out in order to determine the effects of levonorgestrel (LNG) and progestin derivatives, alone and in combination with melatonin (MEL), on the plasma oxidant-antioxidant system,...
The Effects of Melatonin on 6-Phosphogluconate Dehydrogenase:An In Vitro and In Vivo Study
Erythrocytes Melatonin 6-Phosphogluconate dehydrogenase In vivo In vitro
2009/6/23
Melatonin is known to influence a variety of biological processes including circadian rhythms, neuroendocrine, and cardiovascular and immune functions as well as thermoregulation. Melatonin is the chi...
Antioxidant Effect of Melatonin in Systemic Circulation of Rats After Unilateral Testicular Torsion
Testis torsion melatonin treatment
2009/6/16
Aim: To investigate the antioxidant effects of melatonin in the systemic circulation of rats after unilateral testicular torsion. Materials and Methods: After the approval of the study by the Local Et...
Inhibition of Endotoxin-Induced Hepatotoxicity by Melatonin in Rats
endotoxin liver melatonin necrosis oxidative stress tumor necrosis factor α
2009/4/29
Bacterial endotoxin or lipopolysaccharide causes extensive damage to various organs including the liver. This is due to an increased production of tumor necrosis factor α induced- reactive interme...
Influence of photoperiod, ambient temperature and melatonin on testosterone synthesis and release during reproductive maturation in male deer mice
photoperiod ambient temperature melatonin testosterone synthesis reproductive maturation male deer mice
2009/2/23
Four experiments were designed to investigate the influence of photoperiod and other environmental factors on androgen production and reproductive maturation in deer mice. Male prairie deer mice (Pe...
Effects of Photoperiod and Subcutaneous Melatonin Implants on the Reproductive Status of Adult White-footed Mice（Peromyscus leucopus）
implant melatonin photoperiod white-footed mouse Peromyscus leucopus testosterone
2009/2/19
The reproductive consequences of photoperiod and melatonin administration were compared in adult white-footed mice (Peromyscus leucopus). Animals were exposed either to a long photoperiod (16 hours ...
Melatonin inhibits the expression of steroidogenic acute regulatory protein and steroidogenesis in MA-10 cells
Melatonin inhibits steroidogenic protein steroidogenesis MA-10 cells
2008/12/26
The effects of melatonin on steroidogenesis and steroidogenic acute regulatory (StAR) protein expression were investigated in MA-10 mouse Leydig tumor cells. MA-10 cells were treated with human chorio...