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Role of pharmacogenomics in pain therapy: focus on opioids
pharmacogenomics pain therapy opioids
2015/4/1
Analgesics, especially opioids, show remarkable inter-individual variability in both efficacy and adverse effect profile. There are many factors that contribute to this variability, including renal an...
Mechanism of stress-induced attenuation of the testicular response to gonadotropin：possible involvement of testicular opioids, a pertussis toxin-sensitive G-protein, and phosphodiesterase
stress-induced attenuation possible involvement testicular opioids pertussis toxin-sensitive G-protein
2009/2/16
This study examined the potential role of testicular opioids, a pertussis toxin (PT)-sensitive G-protein, and phosphodiesterase in mediating the inhibitory effect of immobilization stress on testi...