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汕头大学医学院药理学课件 gene polymorphism and drug and disease[1]
汕头大学医学院 药理学 课件 gene polymorphism and drug and disease[1]
2014/6/25
汕头大学医学院药理学课件 gene polymorphism and drug and disease[1]。
Association between MDR1 C3435T Gene Polymorphism and Acute Lymphoblastic Leukemia (ALL) in Iranian Population
P-glycoprotein MDR1 Acute lymphoblastic leukemia C3435T polymorphism
2015/9/21
Background: P-glycoprotein (P-gp), an ATP-dependent efflux pump, is a membrane protein encoded by MDR1 gene. P-gp has an important role in protection of the cell against xenobiotics and toxic compound...
Association of Methylenetetrahydrofolate Reductase gene Polymorphism (C677T) with Metabolic Syndrome in an Iranian Population: Tehran Homocysteine Survey
MTHFR Metabolic syndrome Population
2009/11/26
Background: The association of MTHFR and metabolic syndrome (MS) has been shown in special groups of diabetic and schizophrenic subjects, but no single study has investigated this relation in metaboli...
emm Gene Polymorphism among Streptococcus pyogenes Isolated from Throat Culture
Streptococcus pyogenes PCR- RFLP emm gene Pharyngitis
2009/11/26
DNA sequencing is the most conclusive method for emm (M protein gene) typing of Streptococcus pyogenes. This method is not a feasible approach in developing countries where streptococcal infection is ...
山东胃癌高低发人群Lewis基因多态性分析Analysis of Lewis Gene Polymorphism in High and Low Incidence Area of Gastric Cancer in Shandong Province
胃癌 高低发人群 Lewis基因多态性
2007/12/30
摘要应用PCR产物直接测序的方法，检测山东省胃癌高发的临朐人群和低发的苍山人群中Lewis基因多态性T59G的分布,旨在探讨山东临朐和苍山地区胃癌发病率显著不同的内在原因，为阐明临朐地区胃癌高发的机制提供实验依据。结果表明,T59G突变个体在临朐和苍山人群中的分布频率分别为34.5%和31.6%，差别无统计学意义，P＞0.05,OR为1.14 （95% CI,0.59~2.19）。提示就此点突变而...
Interferon-Gamma Gene Polymorphism in Iranian Patients with Multiple Sclerosis
Gene Polymorphism Interferon Multiple Sclerosis
2010/2/4
Interferon- gamma (IFN- γ) is an important immune regulator and inflammatory cytokine which is implicated in the pathogenesis of multiple sclerosis (MS). A single nucleotide polymorphism, T to A, at p...