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First Report on Isolation and Characterization of Leishmania major from Meriones hurrianae (Rodentia: Gerbillidae) of A Rural Cutaneous leishmaniasis Focus in South-Eastern Iran
Meriones hurrianae Leishmania major Molecular Characterization RAPD-PCR Reservoir Host Iran
2015/10/8
Background: Zoonotic Cutaneous Leishmaniasis (ZCL) is an endemic health problem in many rural areas of Iran, with doubled number of incidences over the last decade. Different species of rodents serve ...
Live logarithmic phase Promastigotes of Leishmania major induced high level of INF-γ but lower level of IL-10 in whole blood culture of healthy individuals
Human Logarithmic Metacyclic Axenic amastigotes
2009/12/30
Stage-specifci developmental forms of Lesihmania major promastigotes were grown in vitro. Procyclic and metacyclic promastigotes were cultured and separated by peanut agglutinin. The axenic amastigote...
Detection of Leishmania major In Naturally Infected Sand Flies Using Semi Nested-PCR
Leishmania major Sand fly Leishmaniasis PCR Iran
2009/12/17
Background: The aim of this study was to assess Leishmania infection in sand fly species from areas where leishmaniasis is endemic. This is important for prediction of the risk and expansion of the di...
Pathogenicity Variations of Susceptibility and Resistance to Leishmania major MRHO/IR/75/ER Strain in BALB/c and C57BL/6 mice
Balb/c C57bl/6 Pathogenicity Iran Leishmania major MRHO/IR/75/ER
2009/12/16
Background: To compare the pathogenicity differences in two susceptible Balb/c and resistant C57bl/6 mice infected with Leishmania major MRHO/IR/75/ER as a prevalent strain of zoonotic cutaneous leish...
The Effect of Alkanna tincturia and Peganum harmala Extracts on Leishmania major (MRHO/IR/75/ER) in vitro
Leishmania major Peganum harmala Alkanna tincturia In-vitro
2009/12/14
Background: Cutaneous leishmaniasis is an important health problem caused by Leishmania spp. As there is no vaccine, drug treatment is the only way to tackle leishmaniasis. In the present study, inhib...
Effect of Methanolic Extracts of Artemisia aucheri and Camellia sinensis on Leishmania major (In Vitro)
Leishmania Artemisia aucheri Camellia sinensis medicinal plant promastigote
2009/6/19
Aim: Infections caused by protozoa of the genus Leishmania are major worldwide health problems with high endemicity in developing countries. The incidence of leishmaniasis has increased in the absence...
Immunological Effects of Leishmania major Secretory and Excre¬tory Products on Cutaneous Leishmaniasis in BALB/c Mice
Excretory-Secretory proteins Balb/C Acetylcholinesterase
2010/4/9
Background: To evaluate the immunological properties of Leishmania major excreted- secreted (E-S) products on the progress of leishmaniasis in susceptible BALB/c mice. Methods: Promastigotes of the Le...
Immunological Effects of Leishmania major Secretory and Excre¬tory Products on Cutaneous Leishmaniasis in BALB/c Mice
Excretory-Secretory proteins Balb/C Acetylcholinesterase
2010/4/9
Background: To evaluate the immunological properties of Leishmania major excreted- secreted (E-S) products on the progress of leishmaniasis in susceptible BALB/c mice. Methods: Promastigotes of the Le...
Emergence of Cutaneous Leishmaniasis due to Leishmania major in a New Focus of Southern Iran
Sand flies Epidemiology Leishmania major Leishmaniasis Vector Iran
2010/4/12
Reports from the health center of Kerman Province, southern Iran showed an increasing of cutaneous leishmaniasis cases in Orzuieh Rural District, southwest of the province in 2003. The report encourag...
Immunosuppressive Activity of Leishmania major Culture Supernatant
Leishmania major Excretory factor Immunosuppressive Amastigote Promastigote
2010/2/4
BALB/c mice are highly susceptible to infection with the protozoan parasite Leishmania major. This susceptibility has been attributed in part to the expansion of Th2 cells and production of their cyto...
EFFECT OF IMMUNOMODULATOR DARAPRIM ON POTENTIATION OF VACCINE PROTECTION OF LEISHMANIA MAJOR IN BALB/c MICE
Daraprim VACCINE PROTECTION MMUNOMODULATOR
2010/5/4
In this study, a crude leishmanial antigen, was prepared by sonicating Leishmania major promastigotes used to induce immunity in BALB/c mice against cutaneous leishmaniasis. Correlation between the ro...