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Immunological Tolerance: Therapeutic Induction
免疫耐受诱导 Immunological Tolerance: Therapeutic Induction
2014/6/24
Protection from the development of autoimmune diseases and acceptance of transplanted organs are due to effective tolerance to self-antigens and alloantigens, respectively. Various immunological strat...
Immunological tolerance refers to a reduction or complete inhibition of the ability of an individual to mount a specific immune response upon immunization.
Introduction of an exogenous antigen into the fetus at the time of repertoire maturation renders the host’s immune system tolerant to that antigen. This view stems from a historical observation of non...
Effects of ketamine and magnesium on morphine induced tolerance and dependence in mice
Morphine Tolerance Withdrawal Magnesium Ketamine
2010/1/5
The goal of this study was to evaluate the effects of ketamine and magnesium on prevention of development of morphine tolerance and dependence in mice. In this study different groups of mice received ...
Tolerance Induction by CD40 Silenced Dendritic Cells through Antisense
Dendritic cell Antisense CD40 Tolerance induction
2015/9/18
Background: One of the valuable tools for inhibiting the specific gene expression is antisense technique. To determine T cell responses, co-stimulatory molecule expression on the antigen presenting ce...
Regulatory T cells in oral and self-tolerance
active suppression autoimmunity interleukin-10 transforming growth factor-beta transgenic mice
2010/11/29
Several mechanisms of immunologic tolerance have been proposed, including deletion, anergy and active suppression. Deletion and anergy have been reported based on data from both in vivo and in vitro e...