搜索结果: 1-9 共查到“基础医学 smooth muscle”相关记录9条 . 查询时间(0.046 秒)
The role of SWI/SNF in regulating smooth muscle differentiation
Brm smooth muscle knockout
2015/5/22
There are many clinical diseases involving abnormal differentiation of smooth muscle, such as atherosclerosis, hypertension and asthma. In these diseases, one important pathological process is the dis...
Differentiation and contractility of colon smooth muscle under normal and diabetic conditions
type 1 diabetes colon STZ
2015/5/22
Intestinal smooth muscle development involves complex transcriptional regulation leading to cell differentiation of the circular, longitudinal and muscularis mucosae layers. Differentiated intestinal ...
Serum response factor-dependent regulation of smooth muscle gene transcription
Smooth muscle cells Gene regulation MicroRNA Chromatin remodeling Serum Response Factor
2015/5/22
Several common diseases such as atherosclerosis, post-angioplasty restenosis, and graft vasculopathies, are associated with the changes in the structure and function of smooth muscle cells. During the...
Synthesis and smooth muscle Calcium channel antagonist effect of Alkyl, Aminoalkyl 1,4-Dihydro-2,6-Dimethyl-4-Nitroimidazole-3,5 Pyridine Dicarboxylates
Ca+² channel antagonist DHP Arylpiperazine
2009/12/29
The discovery that 1,4-dihydropyridine (DHP) class of calcium channel antagonist inhibits the Ca+² influx represented a major therapeutic advance in the treatment of cardiovascular diseases such ...
Expression and Function of the Inducible Costimulator Ligand B7-H2 in Human Airway Smooth Muscle Cells
airway inflammation airway smooth muscle cells B7-H2 DNA synthesis inducible costimulator
2010/11/16
The data demonstrate that ASM cells express functionally active B7-H2, CD40 and OX40L and suggest that B7-H2-dependent signaling may play an active role in a proliferative response rather than in cyto...
Airway Smooth Muscle and Asthma
airway remodelling airway smooth muscle asthma extracellular matrix inflammation
2010/11/19
The airway smooth muscle is the key determinant of airway narrowing in asthma but its function in the absence of disease is unknown. Evidence for an intrinsic abnormality in the muscle in asthma is on...
Benidipine hydrochloride increases calcified nodule formation in the bovine aortic smooth muscle cell cultures
Benidipine hydrochloride Vascular calcification
2010/4/6
Arterial calcification, a regulated process similar to ossification in bone, is common in atherosclerosis. A subpopulation of bovine aortic media cells, have osteoblastic characteristics and form spon...
Mechanical strain-induced DNA synthesis and cell proliferation in human airway smooth muscle cells through extracellular signal-regulated kinase
airway smooth muscle cell extracellular signal-regulated kinase mechanical strain
2010/11/25
An increased airway muscle content is one of the characteristic features of airway remodeling. Proinflammatory substances, growth factors and mechanical strain promote airway muscle cell proliferation...
Inhalant corticosteroids inhibit mechanical strain-induced RANTES and eotaxin production by human airway smooth muscle cells
airway smooth muscle cells eotaxin inhaled corticosteroids mechanical strain RANTES
2010/11/24
The results showed that: (i) mechanical strain, including stretch and compression, stimulated ASM cells to produce RANTES and eotaxin; and (ii) FP and BUD inhibited mechanical strain-induced and TNF-α...