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First Report on Isolation and Characterization of Leishmania major from Meriones hurrianae (Rodentia: Gerbillidae) of A Rural Cutaneous leishmaniasis Focus in South-Eastern Iran
Meriones hurrianae Leishmania major Molecular Characterization RAPD-PCR Reservoir Host Iran
2015/10/8
Background: Zoonotic Cutaneous Leishmaniasis (ZCL) is an endemic health problem in many rural areas of Iran, with doubled number of incidences over the last decade. Different species of rodents serve ...
Live logarithmic phase Promastigotes of Leishmania major induced high level of INF-γ but lower level of IL-10 in whole blood culture of healthy individuals
Human Logarithmic Metacyclic Axenic amastigotes
2009/12/30
Stage-specifci developmental forms of Lesihmania major promastigotes were grown in vitro. Procyclic and metacyclic promastigotes were cultured and separated by peanut agglutinin. The axenic amastigote...
RELIMINARY STUDIES OF THE EFFECT OF LAVAMISOLE ON THE IMMUNE RESPONSE OF MICE INFECTED WITH LEISHMANIA
LAVAMISOLE IMMUNE RESPONSE MICE INFECTED LEISHMANIA
2009/12/30
The susceptibility of various strains of mice to infection by Leishmania tropica (major) was recently studied in this laboratory. The infection in A/J, C3H, CBA, AKR/J, AKR/CU, and C57B1 mice (the sem...
Detection of Leishmania major In Naturally Infected Sand Flies Using Semi Nested-PCR
Leishmania major Sand fly Leishmaniasis PCR Iran
2009/12/17
Background: The aim of this study was to assess Leishmania infection in sand fly species from areas where leishmaniasis is endemic. This is important for prediction of the risk and expansion of the di...
Flow Cytometric Analysis of Leishmania Reactive CD4+/CD8+ Lymphocyte Proliferation in Cutaneous Leishmaniasis
CFSE CD4+/CD8+ T cells Proliferation Cutaneous leishmaniasis
2009/12/17
Background: Determination of the division history of T cells in vitro is helpful in the study of effector mechanisms against infections. Technique described here uses the intracellular fluorescent lab...
The Effect of Alkanna tincturia and Peganum harmala Extracts on Leishmania major (MRHO/IR/75/ER) in vitro
Leishmania major Peganum harmala Alkanna tincturia In-vitro
2009/12/14
Background: Cutaneous leishmaniasis is an important health problem caused by Leishmania spp. As there is no vaccine, drug treatment is the only way to tackle leishmaniasis. In the present study, inhib...
Effect of Methanolic Extracts of Artemisia aucheri and Camellia sinensis on Leishmania major (In Vitro)
Leishmania Artemisia aucheri Camellia sinensis medicinal plant promastigote
2009/6/19
Aim: Infections caused by protozoa of the genus Leishmania are major worldwide health problems with high endemicity in developing countries. The incidence of leishmaniasis has increased in the absence...
Immunological Effects of Leishmania major Secretory and Excre¬tory Products on Cutaneous Leishmaniasis in BALB/c Mice
Excretory-Secretory proteins Balb/C Acetylcholinesterase
2010/4/9
Background: To evaluate the immunological properties of Leishmania major excreted- secreted (E-S) products on the progress of leishmaniasis in susceptible BALB/c mice. Methods: Promastigotes of the Le...
Immunological Effects of Leishmania major Secretory and Excre¬tory Products on Cutaneous Leishmaniasis in BALB/c Mice
Excretory-Secretory proteins Balb/C Acetylcholinesterase
2010/4/9
Background: To evaluate the immunological properties of Leishmania major excreted- secreted (E-S) products on the progress of leishmaniasis in susceptible BALB/c mice. Methods: Promastigotes of the Le...
The Seminested PCR Based Detection of Leishmania infantum Infection in Asymptomatic Dogs in a New Endemic Focus of Visceral Leishmaniasis in Iran
Leishmania infantum Dogs Iran
2010/4/8
Visceral Leishmaniasis (Kala-azar) is a serious health problem in some northern and south western parts of Iran. The incidence of kala-azar caused by Leishmania infantum has recently increased in Nour...
Emergence of Cutaneous Leishmaniasis due to Leishmania major in a New Focus of Southern Iran
Sand flies Epidemiology Leishmania major Leishmaniasis Vector Iran
2010/4/12
Reports from the health center of Kerman Province, southern Iran showed an increasing of cutaneous leishmaniasis cases in Orzuieh Rural District, southwest of the province in 2003. The report encourag...
Leishmania tropica:Another Etiological Agent of Canine Visceral Leishmaniasis in Iran
Canine visceral leishmaniasis Molecular methods L.tropica
2010/4/7
Background: Dogs have been previously reported to be reservoirs of Leishmania infantum as the etiological agent of human visceral leishmaniasis in Iran. We report a case of canine visceral leishmanias...