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Statistical design considerations applicable to clinical trials of iodine supplementation in pregnant women who may be mildly iodine deficient
clinical trials iodine supplementation outcomes measurement pregnancy statistical methods
2018/12/14
No large, randomized, placebo-controlled trial of iodine supplementation in pregnant women in a region of mild or moderate iodine deficiency has been completed in which a primary outcome measure was a...
Ethical issues around phase I and phase III clinical trials in cancer
cancer Ethical issues
2017/4/10
The results of phase III (randomised) cancer clinical trials underpin evidence-based clinical practice. A standard comparator (control arm) is crucial so that the real value of an intervention can be ...
Project Management of Randomized Clinical Trials:A Narrative Review
Clinical Trial Project Management Trial Manager Principal Investigator Study Protocol
2015/11/9
Context: A well-structured protocol for a clinical trial may be able to answer clinical questions, but it cannot be deemed enough to ensure success in the face of incompetent management of time as wel...
People’s experiences of taking part in clinical trials have been captured in a new section of www.healthtalkonline.org, the award-winning patient website based on Oxford University research.The online...
Pfizer Stops All Torcetrapib Clinical Trials in Interest of Patient Safety
Patient Safety cardiovascular
2006/12/26
On December 2, 2006, FDA was notified that Pfizer will suspend a large, Phase 3 trial evaluating the investigational cardiovascular therapy torceptrapib/atorvastatin (T/A) due to an increased rate of ...