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探讨64层螺旋CT(spiral CT, SCT)低剂量双相扫描肺密度测定在慢性阻塞性肺部疾病(chronic obstructive pulmonary disease, COPD)患者肺功能评价中的应用价值。方法:选择经临床肺功能检查确诊的COPD患者36例(COPD组)和30例无任何心肺疾患且胸部CT检查正常的健康体检者(正常对照组)。两组研究对象均采用德国Siemens SOMATOM S...
Bronchodilator Efficacy of Single Doses of Indacaterol in Japanese Patients with COPD: A Randomised, Double-Blind, Placebo-Controlled Trial
beta2-agonists bronchodilator COPD efficacy indacaterol
2010/11/12
In the Japanese COPD population studied, single doses of indacaterol (150, 300, and 600μg) provided sustained 24-h bronchodilation, with onset of action within 5 min post-dose. All doses were well tol...
Correlation between Peripheral Blood T-cell Profiles and Clinical and Inflammatory Parameters in Stable COPD
chronic obstructive pulmonary disease correlation exhaled nitric oxide Tc1/Tc2 transfer coefficient
2010/11/12
There was a significantly increased proportion of IFN-γ-producing and IL-4-producing CD8+ T cells in patients with COPD compared with control subjects (median [IQR] 73.6% [63.9%-80.7%] vs 62.0% [45.6%...
Asthma and COPD are complex diseases with strong genetic and environmental components. These common pulmonary diseases have both different and similar clinical features. Molecular genetic techniques a...