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Production of endothelin by canine prostatic epithelial cells and its stimulatory effects on their growth
Canine prostate ETB receptors cell growth
2009/2/18
The current study has been designed to explore expressions of endothelin (ET) receptors and ETs in the canine prostate and the effect of ETs on canine prostatic epithelial cells. ET receptors were c...
Effects of endothelin-1 on the rat testicular vasculature
endothelin-1 rat testicular vasculature
2009/2/16
Endothelin-1 (ET-1), a well-known vasoconstrictor substance, is present in the testis but its functional role is unknown. The present study was undertaken to elucidate whether ET-1 may influence tes...
We have previously found the presence of endothelin (ET) receptor and ET-like immunoreactivity in rat testis. We now extend our studies from rat to human testis. We found expression of a specific tr...
Pilot study of the endothelin-A receptor selective antagonist BMS-193884 for the treatment of erectile dysfunction
Pilot study endothelin-A receptor treatment erectile dysfunction
2008/12/1
Endothelins have been postulated to be important regulators of penile erectile function. The endothelin-A receptor antagonist BMS-193884 was evaluated as a treatment for mild-to-moderate erectile dysf...