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Reproductive aging in the Brown Norway rat is characterized by accelerated germ cell apoptosis and is not altered by luteinizing hormone replacement
Brown Norway rat accelerated germ cell apoptosis luteinizing hormone replacement
2009/2/18
Reproductive aging in the male Brown Norway (BN) rat is characterized by decreased Leydig cell steroidogenesis associated with seminiferous tubule dysfunction. This could be a result of a combination ...
Heat stress causes testicular germ cell apoptosis in adult mice
Spermatogenesis testis cryptorchidism
2009/2/17
An investigation was undertaken to determine whether the germ-cell loss associated with exposure of the testis to abdominal temperature occurs by apoptosis. Using an adult-mouse model of experimenta...
Influence of a Leptin Deficiency on Testicular Morphology, Germ Cell Apoptosis, and Expression Levels of Apoptosis-Related Genes in the Mouse
Spermatogenesis seminiferous tubules testis cytomorphometry micro array
2008/12/24
Leptin-deficient (ob/ob) male mice are morbidly obese and exhibit impaired reproductive function. The objective of this study was to assess the effect of a leptin deficiency on testicular morphology...
Overexpression of Endothelial Nitric Oxide Synthase in Transgenic Mice Accelerates Testicular Germ Cell Apoptosis Induced by Experimental Cryptorchidism
Immunoblotting TUNEL spermatocytes spermatids spermatogonia
2008/12/23
Surgical induction of cryptorchidism in experimental animals causes testicular germ cell apoptosis and infertility. The mechanisms of germ cell apoptosis have been associated with oxidative stress o...
Mild Testicular Hyperthermia Induces Profound Transitional Spermatogenic Suppression Through Increased Germ Cell Apoptosis in Adult Cynomolgus Monkeys (Macaca fascicularis)(
Azoospermia germ cell death heat primate spermatogenesis
2008/12/15
We have previously demonstrated that mild testicular hyperthermia induces stage-specific and germ cell—specific apoptosis in rat and mouse testes. The objectives of this pilot study were to examine wh...
DNA Replication and Germ Cell Apoptosis During Spermatogenesis in the Cat
Spermatogonia spermatocytes spermatogenic stages DNA synthesis programmed cell death
2008/12/5
Stages at which DNA synthesis and germ cell death take place have recently been found to be equivalent in rabbits and rats. Preservation of the timing of these processes in different orders of mamma...
Deoxyribonucleic acid replication and germ cell apoptosis during spermatogenesis in the rabbit
Deoxyribonucleic acid replication germ cell apoptosis spermatogenesis rabbit
2008/12/2
A deeper understanding of the occurrence of some events, such as DNA replication or germ cell apoptosis during spermatogenesis, is important for improving our understanding of seminiferous epitheliu...
P53 and Fas are sequential mechanisms of testicular germ cell apoptosis
P53 Fas sequential mechanisms testicular germ cell apoptosis
2008/12/1
Testicular germ cell apoptosis in the cryptorchid testis is induced by abdominal heat stress. p53-dependent apoptosis appears responsible for the initial phase of germ cell loss in experimental cryp...