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Circadian variation in testosterone, sex hormone-binding globulin, and calculated non-sex hormone-binding globulin bound testosterone in healthy young and elderly men
Circadian variation testosterone sex hormone-binding globulin healthy young and elderly men
2009/2/23
The circadian pattern in levels of serum total testosterone (T) in men becomes blunted with normal aging. However, because T not bound to sex hormone-binding globulin (non-SHBG-T) is felt to be a be...
Indomethacin and oxaprozin lower seminal prostaglandin levels but do not influence sperm motion characteristics and serum hormones of young healthy men in a placebo-controlled double-blind trial
seminal prostaglandin levels sperm motion characteristics serum hormones young healthy men
2009/2/23
To evaluate the influence of indomethacin and oxaprozin on reproductive function in healthy young men, 34 volunteers with normal semen parameters were recruited. In a randomized double-blind design,...
Effects of dietary selenium on sperm motility in healthy men
Semen volume hypothyroidism nutrition selenium
2008/12/29
A deficiency of dietary selenium leads to immotile, deformed sperm and infertility in rats, whereas supplementation of the diet with selenium compounds has been associated with both beneficial and d...
Have sperm counts deteriorated over the past 20 years in healthy, young Japanese men? Results from the Sapporo area
sperm counts deteriorated healthy young Japanese men Sapporo area
2008/12/26
Changes in semen quality of healthy men is a controversial issue throughout the world. It is suspected that many chemical endocrine disrupters may affect the quality of semen. Although exposure to the...
Semen quality and human fertility：a prospective study with healthy couples
Semen quality human fertility prospective study healthy couples
2008/12/25
Measures of semen quality are used as surrogate measures of male fertility in clinical andrology, reproductive toxicology, epidemiology, and risk assessment. However, only limited data are av...
Exogenous Testosterone Alone or With Finasteride Does Not Improve Measurements of Cognition in Healthy Older Men With Low Serum Testosterone
Aging testosterone replacement memory visual spatial function
2008/12/24
Testosterone (T) levels decline as men age, but it is unclear whether this has an effect on cognition. Some studies indicate that lower T levels are associated with memory loss; thus, maintaining a...
Pharmacokinetics of Testosterone Undecanoate Injected Alone or in Combination With Norethisterone Enanthate in Healthy Men
Azoospermia oligozoospermia male contraception
2008/12/24
Long-acting injectable testosterone undecanoate (TU) is a promising androgen for male hormonal contraception. As a prerequisite for a planned multicenter male contraceptive efficacy study, we studie...
Inhibin-B Levels in Healthy Young Adult Men and Prepubertal Boys：Is Obesity the Cause for the Contemporary Decline in Sperm Count Because of Fewer Sertoli Cells?
Male infertility testis puberty
2008/12/24
Inhibin-B is a heterodimeric glycoprotein produced by Sertoli cells. Although inhibin-B levels are low when seminiferous tubules are damaged, studies in normal monkeys reveal that inhibin-B le...
Effect of Antioxidant Intake on Sperm Chromatin Stability in Healthy Nonsmoking Men
Fertility spermatozoa nutrition oxidative stress DNA fragmentation
2008/12/23
Oxidative stress is detrimental to sperm function and a significant factor in the etiology of male infertility. This report examines the association between dietary and supplementary intake of the...
Melatonin Administration Alters Semen Quality in Healthy Men
Estradiol seminal plasma sperm analysis testosterone
2008/12/8
The role of melatonin in the regulation of reproduction in humans is unknown. We conducted a 6-month, double-blind, crossover study of a daily treatment dose of 3 mg melatonin or placebo given orall...
Contraceptive Steroids Influence the Hemostatic Activation State in Healthy Men
Cardiovascular risk gestagens hemostasis hormonal male contraception testosterone
2008/12/5
Hormonal contraception for men requires administration of testosterone and gestagens. The effects of a long-acting testosterone ester and 2 different progestins on hemostatic activation parameters w...
Aneuploidy and chromosome breakage in swim-up versus unprocessed semen from twenty healthy men
Aneuploidy chromosome breakage unprocessed semen twenty healthy men
2008/12/2
Toxicological and epidemiological studies have investigated several factors that are believed to induce cytogenetic damage in human sperm cells in an effort to estimate heritable risk to future gene...