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The differential effects of the indazole-carboxylic acid derivative, tolnidamine, on Sertoli cell protein secretion
Indazole-carboxylic acids tolnidamine antispermatogenic agents Sertoli cell
2009/2/23
The indazole-carboxylic acid derivative tolnidamine (TOL) has marked antispermatogenic activity in rats. Previous morphological and biochemical studies indicate that Sertoli cells are one of the tar...
Leydig cell and extracellular matrix effects on Sertoli cell function：biochemical and morphologic studies
Leydig cell extracellular matrix Sertoli cell function
2009/2/23
The reciprocal influence between Leydig and Sertoli cells prepared from pig testis were studied by coculture of both types of cells in either plastic dishes or dishes coated with basement membrane...
The action of calcitonin on the TM4 Sertoli cell line and on rat Sertoli cell-enriched cultures
TM4 Sertoli cell line rat Sertoli cell-enriched cultures
2009/2/23
The effects of synthetic salmon calcitonin on primary Sertoli cell-enriched cultures and on an established cell line (TM4 cells, derived from immature mouse Sertoli cells) were studied. Synthetic ...
Transferrin secretion in response to different modes of FSH stimulation and cycloheximide in superfused Sertoli cell cultures
Transferrin secretion FSH stimulation cycloheximide superfused Sertoli cell cultures
2009/2/23
The influence of different modes of FSH stimulation and cycloheximide on transferrin secretion by rat Sertoli cells was investigated using a superfusion culture system. Sertoli cells from 18-day-old...
Evidence for age-dependent changes in Sertoli cell androgen receptor concentration
age-dependent changes Sertoli cell receptor concentration
2009/2/23
Cytosol and nuclear receptor concentrations in Sertoli cells isolated from the testes of 15-, 25-, and 35-day-old rats were measured using hydroxylapatite separation procedures. In these cells the m...
Sertoli cell junctional complexes in gossypol-treated neonatal and adult guinea pigs
Sertoli cell gossypol-treated neonatal adult guinea pigs
2009/2/23
The effect of gossypol, an experimental male contraceptive agent, on the development and maintenance of the blood-testis barrier was determined by feeding gossypol daily to prepubertal and adult gui...
Polarized Sertoli cell functions in a new two-compartment culture system
Polarized Sertoli cell functions new two-compartment culture system
2009/2/23
Sertoli cells in vivo are highly polarized and interact with the inner (tubular) and outer (interstitial) fluids. To simulate this condition in vitro we developed a two-compartment culture system ...
Role of the pineal in the alteration of hamster Sertoli cell responsiveness to FSH during testicular regression
pineal hamster Sertoli cells testicular regression short photoperiod optic enucleation
2009/2/20
Testicular regression was induced in adult hamsters by optic enucleation, short photoperiod, or melatonin injections. The melatonin injected group, while undergoing testicular regression, showed a q...
Modification of Sertoli Cell Responsiveness to FSH by Cryptorchidism and Hypophysectomy in Immature and Adult Rats
rat cryptorchidy hypophysectomy cAMP Sertoli cell
2009/2/19
Cryptorchid or hypophysectomized rats were used as models to examine the possible relationships between germ cell development and gonadotropins in the agerelated decline in the responsiveness of t...
In Vitro Gonadotropin Stimulation of Bovine Sertoli Cell Ornithine Decarboxylase Activity
ornithine decarboxylase Sertoli cell gonadotropins bovine calf
2009/2/19
The activity of ornithine decarboxylase (ODC) was determined in primary cultures of bovine Sertoli cells after gonadotropin stimulation in vitro. A significant increase in both ODC activity and putr...
Pure Sertoli Cell Cultures：A New Model for the Study of Somatic-Germ Cell Interactions
cell cultures Sertoli cell germ cell
2009/2/19
A new technique involving a brief hypotonic treatment was developed for obtaining pure rat Sertoli cell cultures. This method for the selective removal of the germ cells present in Sertoli cell enri...
Concentrations of Immunoreactive Inhibin in Seminal Plasma and Serum from Normospermic, Oligospermic, Vasectomized, Klinefelter's Syndrome, and Sertoli-cell—only Syndrome Subjects
inhibin radioimmunoassay seminal plasma serum
2009/2/18
Semen samples and blood were collected from 57 men: 23 normospermic, 20 oligospermic, 10 vasectomized, two with Klinefelter's syndrome, and two with Sertoli-cell—only syndrome. Inhibin was measure...
Effect of N-acetylsphingosine (C2) and the ceramidase inhibitor (1S,2R)-D-erythro-2-（N-myristoylamino）-1-phenyl-1-propanol on the regulation of Sertoli cell function
N-acetylsphingosine (C2) (1S,2R)-D-erythro-2-（N-myristoylamino）-1-phenyl-1-propanol Sertoli cell function
2009/2/18
In the present study, a possible role of ceramide in the regulation of Sertoli cell function was investigated. Intracellular ceramide levels were increased by adding N-acetylsphingosine (C2) or by i...
Potential daily sperm production, Sertoli cell number, and seminiferous tubule characteristics in beef bulls fed conventional or gossypol-enriched diets
Potential daily sperm production Sertoli cell number seminiferous tubule characteristics
2009/2/18
The objective of this study was to determine the amount of germ cell degeneration throughout spermatogenesis in the bull and to determine if gossypol-enriched diets enhance that degeneration. Twenty...
Evidence that in a physiological setting Sertoli cell number is the major determinant of circulating concentrations of inhibin B in the adult male rhesus monkey（Macaca mulatta）
Sertoli cell number circulating concentrations inhibin B adult male rhesus monkey
2009/2/18
The relationship between changes in Sertoli cell number and function and changes in circulating inhibin B concentrations was investigated following unilateral orchidectomy (UO) in the adult rhesus...