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Weight reduction reduces bone mineral density (BMD) and increases the risk of osteoporosis.
Dietary fat and energy have been implicated as factors controlling circulating total and LDL-cholesterol concentrations. Whether these factors work independently or synergistically in regulating hu...
Plasma leptin in humans is subject to both longand short-term regulation; it correlates with indexes of body fat that can only change slowly. However, short-term fasting causes large and rapid decr...
Background: An adaptive decrease in energy expenditure (EE) in response to 6 mo of severely restricted energy intake was shown in a classic semistarvation study—the Minnesota experiment. Objective:...
The concept of a body weight set point, determined predominantly by genetic mechanisms, has been proposed to explain the poor long-term results of conventional energyrestricted diets in the treatme...

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