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A high phylloquinone intake is required to achieve maximal osteocalcin γ-carboxylation
Vitamin K phylloquinone osteocalcin undercarboxylated osteocalcin γ-carboxylation
2016/12/19
Background: Dietary vitamin K is usually inadequate to maximize serum osteocalcin γ-carboxylation. Phylloquinone supplementation increases osteocalcin γ-carboxylation; however, the amount require...
Bone mineral contents and plasma osteocalcin concentrations of Gambian children 12 and 24 mo after the withdrawal of a calcium supplement
Bone mineral accretion calcium children Gambia osteocalcin osteoporosis
2016/12/19
Background: Our randomized, placebo-controlled supplementation study of 160 rural Gambian children aged 8.3–11.9 y showed that an increase in calcium intake of 714 mg/d for 12 mo resulted in a 5%...
Vitamin K supplementation reduces serum concentrations of under--carboxylated osteocalcin in healthy young and elderly adults1
Vitamin K phylloquinone osteocalcin, undercarboxylated osteocalcin ucOC bone turnover osteoporosis
2016/6/8
Background: Subclinical vitamin K insufficiency, manifested
by under--carboxylation of the bone matrix protein osteocalcin,
may be common.
Objective: Our objective was to delineate the prevalence o...