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Background RNA-binding proteins (RBPs) play important roles in cellular homeostasis by controlling gene expression at the post-transcriptional level. Results We explore the expression of more than 800...
The Calcium Integrin Binding protein (CIB) has been identified as interacting specifically with the cytoplasmic tail of the integrin αIIb domain to induce receptor activation and integrin αIIbβ3 media...
A predictive method for the evaluation of peptide binding in pocket 1 of HLA-DR1 via global minimization of energy interactions.
The mammalian metallothioneins (MT) are effectively induced in response to the various heavy metal ions. The inductions of these genes are mainly based on the transcriptional activation and the metal ...
Copper is an essential micronutrient with numerous cellular functions. Previous studies have demonstrated that copper deficiency in P19 embryonal carcinoma cells by using a copper depletor, bathocupro...
The biological function of nuclear copper in mammalian cells is poorly understood because little is known about specific binding protein(s) for nuclear copper. We recently purified that p54nrb/Non-POU...
Our recent studies have demonstrated that the middle domain of N-acetyl-D-glucosamine (GlcNAc) 2-epimerase participates in the specificity for and binding of nucleotides. To identify the residue con...
Geldanamycin, a heat-shock protein 90 (Hsp90)-binding agent, modulates various cellular activities. The present study found that, although geldanamycin by itself had no effect on thymocyte viability...
The FRET signal was maintained in the presence of 10-,20-,40-, and 60-mer DNA inhighionic-strength buffer,showing that the driving force for the desorption is electrostatic repulsion between the boun...

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