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Geldanamycin, a heat-shock protein 90-binding agent, induces thymocyte apoptosis through destabilization of Lck in presence of 12-O-tetradecanoylphorbol 13-acetate
Geldanamycin heat-shock protein 90-binding agent destabilization of Lck 12-O-tetradecanoylphorbol 13-acetate
2009/3/2
Geldanamycin, a heat-shock protein 90 (Hsp90)-binding agent, modulates various cellular activities. The present study found that, although geldanamycin by itself had no effect on thymocyte viability...