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Anticancer drug discovery:structures of KDM5 histone demethylase inhibitors
Anticancer drug KDM5 histone demethylase inhibitors
2016/8/1
When doctors hurl toxic death at cancer cells, often a few will survive and come back. A family of enzymes called KDM5 histone demethylases is emerging as important for this resilience, and drugs that...
Polarographic determination of anticancer drug vitamin K3 with direct and indirect methods/application to serum and K3 injection solution
Vitamin K3 sulfite direct indirect differential pulse polarography
2011/4/6
In this work, direct and indirect methods for determination of vitamin K3 were developed using differential pulse polarography. The reaction between sulfite and the quinone (Q) form of vitamin K3 was ...
Preparation and characterization of anticancer drug-loaded implantable PLGA microparticles
characterization Preparation anticancer drug-loaded implantable
2010/10/18
This article describes the preparation and characterization of anticancer drug-loaded poly(lactide-co-glycolide) (PLGA) microparticles. PLGA microparticles loaded with doxorubicin HCl (DOX) were prepa...
Voltammetry of the Anticancer Drug Mitoxantrone and DNA
Mitoxantrone Biosensors DNA Voltammetry Intercalation
2010/4/22
The interaction of mitoxantrone (MTX) with calf thymus double-stranded DNA (dsDNA) and calf thymus single-stranded DNA (ssDNA) was studied electrochemically by using differential pulse voltammetry (DP...