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Evaluation of the Energetics of the Concerted Acid-Base Mechanism in Enzymatic Catalysis:The Case of Ketosteroid Isomerase
Energetics Concerted Acid-Base Mechanism Enzymatic Catalysis Ketosteroid Isomerase
2016/5/25
Structures of enzymes invariably reveal the proximity of acidic and basic residues to reactive sites on the substrate, so it is natural and common to suggest that enzymes employ concerted mechanisms t...