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中山大学肿瘤防治中心“盐酸安罗替尼联合STUPP方案治疗新诊断胶质母细胞瘤 (GBM) 患者随机、双盲、多中心II 期临床研究”项目启动会顺利召开(图)
盐酸安罗替尼;STUPP方案;胶质母细胞瘤;双盲
2021/9/22
6月10日,中山大学肿瘤防治中心召开“盐酸安罗替尼胶囊联合STUPP方案对比标准STUPP方案治疗新诊断胶质母细胞瘤的随机、双盲、多中心II期临床试验”启动会。中肿神经外科、放疗科、病理科和影像科的专家参加了本次启动会议,正大天晴药业集团股份有限公司代表在线上参会。会议由研究项目PI中肿神经外科陈忠平教授主持。
启动会现场(图一)
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2021年6月10日,中山大学肿瘤防治中心召开“盐酸安罗替尼胶囊联合STUPP方案对比标准STUPP方案治疗新诊断胶质母细胞瘤的随机、双盲、多中心II期临床试验”启动会。中肿神经外科、放疗科、病理科和影像科的专家参加了本次启动会议,正大天晴药业集团股份有限公司代表在线上参会。会议由研究项目PI中肿神经外科陈忠平教授主持。
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近日,山东大学药学院姜新义教授团队构建了一种可注射的仿生纳米免疫调节剂-水凝胶超结构递药系统,并成功应用于IDH1突变型恶性脑胶质瘤的术后免疫治疗。该水凝胶系统一方面可增加T细胞的激活和脑内招募;另一方面可调控氨基酸代谢消除Treg细胞的抑制作用,从而重塑“热”的肿瘤杀伤免疫微环境阻止术后胶质瘤的复发。该研究成果以“Immunostimulant hydrogel for the inhibiti...
TERTp和1p/19q对顺铂联合替莫唑胺同期放化疗治疗MGMT启动子未甲基化GBM的预后影响
胶质母细胞瘤 O6-甲基鸟嘌呤-DNA甲基转移酶启动子未甲基化 端粒酶逆转录酶 1p/19q 顺铂 替莫唑胺
2020/6/11
讨TERTp和1p/19q不同表型对DDP联合TMZ同期放化疗治疗新诊断 MGMT启动子未甲基化GBM的预后影响。方法回顾性分析73例新诊断MGMT启动子未甲基化的GBM的临床资料,均接受DDP联合TMZ同期放化疗,行TERTp和1p/19q检测,分析TERTp和1p/19q不同表型的临床特征、副反应、PFS和OS。结果根据TERTp分为 TERTp wt 30例和TERTp mut 43例,根据...
Constraints on the Synchrotron Shock Model for the Fermi GBM Gamma-Ray Burst 090820A
Constraints Synchrotron Shock Model Fermi GBM Gamma-Ray Burst 090820A
2011/10/18
Discerning the radiative dissipation mechanism for prompt emission in Gamma-Ray Bursts (GRBs) requires detailed spectroscopic modeling that straddles the $\nu F_{\nu}$ peak in the 100 keV - 1 MeV rang...
Peculiarly Narrow SED of GRB 090926B with MAXI and Fermi/GBM
gamma rays: bursts — methods: data analysis
2011/10/19
The monitor of all-sky X-ray image (MAXI) Gas Slit Camera (GSC) on the International Space Station (ISS) detected a gamma-ray burst (GRB) on 2009, September 26, GRB\,090926B. This GRB had extremely ha...
We present our temporal and spectral analyses of 29 bursts from SGR J0501+4516, detected with the Gamma-ray Burst Monitor onboard the Fermi Gamma-ray Space Telescope during the 13 days of the source a...
Searching for Needles in Haystacks - Using the Fermi/GBM to find GRB gamma-rays with the Fermi/LAT Detector
High Energy Astrophysical Phenomena (astro-ph.HE)
2010/12/27
From the launch of the Fermi Gamma-ray Space Telescope to July 9, 2010, the Gamma-ray Burst Monitor (GBM) has detected 497 probable GRB events. Twenty-two of these satisfy the simultaneous requirement...