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An IL-4-dependent macrophage-iNKT cell circuit resolves sterile inflammation and is defective in mice with chronic granulomatous disease
macrophage-iNKT cel chronic granulomatous disease
2015/5/21
The immune system initiates tissue repair following injury. In response to sterile tissue injury, neutrophils infiltrate the tissue to remove tissue debris and subsequently undergo apoptosis. Proper c...
Granulomatous metritis caused by suspected Dirofilaria immitis in a dog: a case report
dog filarid granuloma larva nematode uterus
2015/4/16
Here we describe a unique uterine mass in a dog with granulomatous lesions caused by filarial larvae from the family Onchocercidae. An 8-year-old female Maltese was presented to a local animal hospita...
Primary Splenic Hodgkin’s Disease in a Patient with Chronic Granulomatous Disease,a Case Report
Chronic granulomatous disease Spleen Hodgkin’s disease
2015/9/21
Here we report a 20-year-old male, a known case of chronic granulomatous disease (CGD), who presented with fever and splenomegaly. After splenectomy, primary splenic Hodgkin’s disease was diagnosed. I...
Autosomal Recessive Chronic Granulomatous Disease,IgA Deficiency and Refractory Autoimmune Thrombocytopenia Responding to Anti-CD20 Monoclonal Antibody
Anti-CD20 Autoimmune thrombocytopenia Chronic granulomatous disease IgA deficiency Primary immunodeficiency diseases
2009/12/17
Immunodeficiency and autoimmune disease may occur concomitantly in the same individual. Some of the immunodeficiency syndromes, especially humoral defects are associated with autoimmune disorders. Hem...
Effect of Corticosteroid Therapy in Esophageal Stricture of a Child with Chronic Granulomatous Disease
Chronic granulomatous disease Corticosteroid Esophageal stricture
2009/12/17
In chronic granulomatous disease (CGD) patients, esophageal stricture is a rare complication and the treatment of choice is still controversial. There are few reports of successful therapy with antibi...
Lymphocytic Bronchiolitis as Presenting Disorder in an Undiagnosed Adult Patient with Chronic Granulomatous Disease
Anthropology human leukocyte antigen human populations Iran
2010/4/27
Chronic Granulomatous Disease (CGD) is a rare primary immunodeficiency disease. Although the most affected patients are diagnosed in childhood, there are several reports of the disease presenting in a...
Clinical and Radiological Aspects of Chronic Granulomatous Disease in Children: A case Series from Iran
Chronic granulomatous disease Children Infection Radiology
2010/2/8
Chronic granulomatous disease (CGD) is a rare disorder of phagocytes, predisposes patients to bacterial and fungal infections. The main purpose of this study was to determine the clinical, radiologica...
CYBB Gene Mutation Detection in an Iranian Patient with Chronic Granulomatous Disease
Chronic Granulomatous Disease CYBB Protein Human Gene
2010/1/29
In this study, we report a mutation in CYBB gene in a patient with X-CGD (diagnosed on the base of family history, NDT test, DHR 123 assay). Mutation in CYBB gene was detected using SSCP analysis (sin...
Gastrointestinal Manifestations of Patients with Chronic Granulomatous Disease
Chronic granulomatous disease infection gastrointestinal disorders
2010/2/4
Chronic Granulomatous Disease (CGD) represents a group of inherited disorders of phagocytic system, manifesting recurrent infections at different sites. The present study was accomplished in order to ...
RESPIRATORY MANIFESTATIONS OF CHRONIC GRANULOMATOUS DISEASE; A CLINICAL SURVEY OF PATIENTS FROM IRANIAN PRIMARY IMMUNODEFICIENCY REGISTRY
Respiratory manifestations Chronic granulomatous disease
2010/4/30
Chronic granulomatous disease represents a group of inherited disorders of phagocytic system wherein recurrent infections are seen at different sites especially in the respiratory system. To determine...