搜索结果: 1-15 共查到“Pharmacological”相关记录21条 . 查询时间(0.125 秒)
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2020年12月13日,中心/实验室杨子峰研究员团队的连花清瘟抗新冠论文《Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2)》被知名药理学杂志《Pharmacological Research》评选为2019/2020年度优秀论文。该论文是中药抗...
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北京大学医学部李子健课题组在Cell系列期刊Trends in Pharmacological Sciences上发表G蛋白偶联受体激活模式文章(图)
北京大学医学部 G蛋白 偶联受体 激活模式 文章
2018/3/14
近日,美国著名出版集团Cell Press旗下的药理学权威期刊Trends in Pharmacological Sciences (TiPS) 在线全文发表了北京大学第三医院李子健课题组题为“New Insights into Modes of GPCR Activation”的文章(原文链接http://www.cell.com/trends/pharmacological-sciences/...
Structure, Function, and Pharmacological Chaperones for Human α-N-Acetylgalactosaminidase
Pure sciences Biological sciences Galactosidase Acetylgalactosaminidase Lysosomal storage disease Pharmacological chaperones Structural biology X-ray crystallography
2014/12/10
Human lysosomal α-N-acetylgalactosaminidase (α-NAGAL) is responsible for the break down of glycolipids and glycopeptides that contain a terminal α-linked N-acetylgalactosamine residues. Deficiency of ...
Pharmacological Chaperoning in Fabry Disease
Pharmacological Chaperone Fabry Disease X-ray Crystallography
2014/12/9
Fabry Disease is an X--‐linked lysosomal storage disorder characterized by a variety of symptoms including hypohydrosis, seizures, cardiac abnormalities, skin lesions, and chronic pain. These symptoms...
Non-Pharmacological Management of The Behavioral And Psychological Symptoms of Dementia
Non-Pharmacological Pharmacological Dementia
2014/10/22
The focus of this change in practice implementation project is to emphasize and encourage the use of non-pharmacological interventions as the first line intervention in managing the Behavioral and Psy...
Efficacy of rehabilitation program in addition to pharmacological treatment during 8 months in Parkinson patients
Parkinson Rehabilitation UPDRS
2013/1/29
To compare 8-month effects of medical treatment plus rehabilitation on UPDRS scores of parkinsonian patients with that of medical treat- ment without rehabilitation. Design: Longtudinal randomized stu...
The Effects of Pharmacological Treatment of ADHD on Children's Health
ADHD evaluation health
2012/10/23
We are the first to investigate longer-term effects of pharmacological treatment of ADHD on children's health. We rely on a difference-in-differences strategy while exploiting Danish register-based pa...
Pharmacological Treatment in Asthma and COPD
asthma bronchodilators COPD inhaled glucocorticosteroids
2010/11/16
Many lines of previous studies have reported that differences and similarities between bronchial asthma (BA) and chronic obstructive pulmonary disease (COPD). The pathological and physiological abnorm...
A system for pharmacological studies in small animals at high pressure
pharmacological animal rat
2009/7/16
A four-liter pressure chamber was constructed for pharmacological experiments in rats; it consisted of the following: 1) a system for repeated, accurate injection; 2) an alternative single-dose inject...
Pharmacological evidence for multiple sites of action of pressure in mice
high pressure nervous syndrome animal mice drug heliox
2009/7/16
The ability of eight diverse pharmacological agents to ameliorate the high pressure nervous syndrome (HPNS) in mice was studied. Data were obtained for the end points: coarse tremors, complete spasms,...
Pharmacological Strategies to Control Post-operative Endodontic Pain
Endodontic treatment Pain control Pharmacology
2009/4/2
Patients typically associate dental care with pain. Pain has both physiological and psychological components. Endodontic post-treatment pain continues to be a significant problem facing the dental p...
Influence of Culture Medium Components on the Pharmacological Effects of Agaricus blazei
Agaricus blazei pharmacological effect sugar cane culture medium
2009/3/6
Differences of the pharmacological effects of Agaricus blazei cultured by various materials were examined. Agaricus blazei mushrooms were prepared on culture media composed by the following five mater...
Influence of a Nucleic Acid-related Substance on the Mycelial Growth and the Pharmacological Effects of Pleurotus nebrodensis
Pleurotus nebrodensis pharmacological effect nucleic acid-related substance
2009/3/4
The influence of a nucleic acid-related substance on Pleurotus nebrodensis cultivation was assessed in terms of mycelial growth and pharmacological effects. The addition of the nucleic acid-related su...
Enhanced pharmacological testing in patients with erectile dysfunction
Enhanced pharmacological testing patients erectile dysfunction
2009/2/13
This study was designed to evaluate the practical use of the combination of a low-dose intracavernous injection test (ICI) and visual erotic stimulation (VES) in the assessment of patients with er...
Triheterocyclic Thiadiazepine Derivatives of Pharmacological Interest: Synthesis of 2-Aryl-4-[p-(2,3-dihydro-5-methyl-2-oxo-1,3,4-oxadiazol-3-yl)phenyl]-6-(un)substituent-1
4-acetylphenylsydnone 1,3-dipolar cycloaddition 1,3,4-thiadiazepine 1,2,4-triazole 1,3,4-oxadiazo-line triheterocycle ring closure condensation Michael addition cardiovascular agent
2007/12/20
摘要 Synthesis of novel thiadiazepine derivatives based on the reactivity of 4-acetylphenylsydnone (1) was reported. The structures of the newly synthesized compounds have been proved by their physical,...