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Multiple vital cellular processes are regulated by specific interactions between proteins and examples of pathways mediated by protein-protein interactions (PPIs) include gene expression, proliferatio...
Investigating Protein-protein Interactions in Live Cells Using Bioluminescence Resonance Energy Transfer
Protein-protein Interactions Live Cells Bioluminescence Resonance Energy Transfer
2015/5/5
Assays based on Bioluminescence Resonance Energy Transfer (BRET) provide a sensitive and reliable means to monitor protein-protein interactions in live cells. BRET is the non-radiative transfer of ene...
Automated Analysis of Fluorescence Microscopy Images to Identify Protein-Protein Interactions
Fluorescence Microscopy Images Interactions
2009/9/8
The identification of protein interactions is important for elucidating biological networks. One obstacle in comprehensive interaction studies is the analyses of large datasets, particularly those con...
HINT: a database of annotated protein-protein interactions and their homologs
homologous interactions interaction families
2010/12/2
Despite the abundance of protein-protein interaction databases currently available online, a source that identifies and lists similar interactions in different species is lacking. The Homologous Inter...