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Regulation of the p53 tumor suppressor gene in the mammary gland and its role in tumorigenesis
Biological sciences p53 Tumor suppressor Mammary gland Tumorigenesis
2015/1/28
Breast cancer is the most frequent tumor type among women. Heightened susceptibility of the breast to tumor development has been associated with early menarche, nulliparity, exposures to ionizing radi...
Hormones, growth factors, and the regulation of tumor suppressor pathways involved in parity -induced protection of breast cancer
Women with breast cancer cases diagnosis and reproduction exogenous hormones ionizing radiation genetic factors
2014/12/11
Despite current advances in understanding breast cancer, in 2007 an estimated 178,480 new cases were diagnosed in female patients in the United States, and an estimated 40,640 deaths will occur due to...
The False Paradigm of RUNX3 Function as Tumor Suppressor in Gastric Cancer
Gastric Cancer RUNX3 Expression Tumor Suppressor Genes
2013/1/29
Gastric cancer (GC) is a major cause of cancer mortality. GC studies that aim to identify relevant oncogenes and tumor suppressor genes (TSGs) are essential for devising effective new therapies. A dec...