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Identification and Functional Analysis of Two Alcohol Dehydrogenase Genes Involved in Catalyzing the Reduction of (Z)‑3-Hexenal into (Z)‑3-Hexenol in Tea Plants (Camellia sinensis)
乙醇脱氢酶 ADH AsODNs Camellia sinensis
2023/4/19
Alcohol dehydrogenase (ADH) is a vital enzyme in the biosynthesis pathway of six-carbon volatiles in plants. However, little is known about its functions in tea plants. Here, we identified two ADH gen...
Overexpression of Sedum alfredii cinnamyl alcohol dehydrogenase increases the tolerance and accumulation of cadmium in Arabidopsis
Sedum alfredii cinnamyl dehydrogenase cinnamyl alcohol cadmium Arabidopsis
2023/6/5
Plant cell walls protect plants from heavy metal stress by resistance, transport and the adsorption process. Cell walls are impregnated with lignin, which enables structural integrity, long-distance w...
Characterization of the Mitochondrial Proteome in Pyruvate Dehydrogenase Kinase 4 Wild-Type and Knockout Mice
Starvation Mitochondria Proteomics PDK4
2015/5/25
The goal of this study was to determine the effect of a PDK4 (pyruvate dehydrogenase kinase isoenzyme 4) knock-out on mitochondrial protein expression. A 2-D gel based mass spectrometry approach was u...
Discovery of novel regulators of aldehyde dehydrogenase isoenzymes
ALDH2 Characterization High-throughput docking approach
2015/5/25
Recent work has shown that specific ALDH isoenzymes can contribute to the underlying pathology of different diseases. Many ALDH isozymes are important in oxidizing reactive aldehydes resulting from li...
The role of pyruvate dehydrogenase kinase in glucose and ketone body metabolism
ketoacidosis hypothermia fatty acid pyruvate carboxylase
2015/5/25
The expression of pyruvate dehydrogenase kinase (PDK) 2 and 4 are increased in the fasted state to inactivate the pyruvate dehydrogenase complex (PDC) by phosphorylation to conserve substrates for glu...
Identification, kinetic and structural characterization of small molecule inhibitors of aldehyde dehydrogenase 3a1 (Aldh3a1) as an adjuvant therapy for reversing cancer chemo-resistance
cyclophosphamide chemosensitivity structure activity relationships cell culture
2015/5/25
ALDH isoenzymes are known to impact the sensitivity of certain neoplastic cells toward cyclophosphamides and its analogs. Despite its bone marrow toxicity, cyclophos-phamide is still used to treat var...
Subcellular Characterization of Porcine Oocytes with Different Glucose-6-phosphate Dehydrogenase Activities
Brilliant Cresyl Blue Embryonic Development Subcellular Characteristics
2016/5/19
The in vitro maturation (IVM) efficiency of porcine embryos is still low because of poor oocyte quality. Although brilliant cresyl blue positive (BCB+) oocytes with low glucose-6-phosphate dehydrogena...
Isolation, cloning and sequence analysis of lactate dehydrogenase gene from Theileria annulata may lead to design of new antitheilerial drugs
Theileria annulata theileriosis antitheilerials lactate dehydrogenase gene cloning
2015/4/15
Theileriosis is a serious animal disease that is transmitted by ticks. Theileria species are tick-borne obligate intracellular protozoan parasites that cause severe and mild infections in their hosts....
Haptoglobin and lactate dehydrogenase measurements in milk for the identification of subclinically diseased udder quarters
haptoglobin LDH milk diagnosis of subclinical mastitis
2015/3/13
Diagnosis of subclinical mastitis is of increasing importance and appropriate detection methods are needed. Both haptoglobin (Hp), an acute phase protein in cattle, as well as lactate dehydrogenase (L...
purification and characterization of glucose 6-phosphate dehydrogenase from rainbow trout (oncorhynchus mykiss) erythrocytes
purification characterization glucose 6-phosphate dehydrogenase
2015/2/5
Glucose 6-phosphate dehydrogenase (D-glucose 6-phosphate: NADP+ oxidoreductase, EC 1.1.1.49; G6PD) from rainbow trout (Oncorhynchus mykiss) erythrocytes was purified, using a simple and rapid method, ...
Expression and processing of xanthin dehydrogenase/oxidase cDNA from African cape buffalo
Biological sciences Xanthin dehydrogenase Syncerus caffer Trypanosome Cape buffalo
2015/1/28
Our lab studies oxidative regulation in defense against extracellular pathogens, especially African Trypanosomes. ^ Trypanosomes are protozoan hemoflagellates. The organisms are transmitted by tsetse ...
Effects of some antibiotics on glucose 6-phosphate dehydrogenase in sheep liver
glucose 6-phosphate dehydrogenase antibiotics sheep liver
2015/1/26
In vitro effects of penicillin, sulbactam, cefazolin, and amikacine on the activity of the enzyme glucose-6-phosphate dehydrogenase in sheep liver were investigated. Glucose 6-phosphate dehydrogenase ...
Discovery of Novel Regulators of Aldehyde Dehydrogenase Isoenzymes
Aldehyde dehydrogenase high-throughput screening computational docking
2015/1/7
Over the past three years we have been involved in high-throughput screening in an effort to discover novel small molecular modulators of aldehyde dehydrogenase (ALDH) activity. In particular, we have...
Effects of Dietary Levels of Glycine, Threonine and Protein on Threonine Efficiency and Threonine Dehydrogenase Activity in Hepatic Mitochondria of Chicks
Threonine Dehydrogenase Threonine Efficiency
2016/5/16
This study was carried out to evaluate the relationship between threonine (Thr) efficiency and Thr dehydrogenase (TDG) activity as an indicator of Thr oxidation on chicks fed with levels of diets (CP ...
Evaluation of Milk Trace Elements, Lactate Dehydrogenase, Alkaline Phosphatase and Aspartate Aminotransferase Activity of Subclinical Mastitis as and Indicator of Subclinical Mastitis in Riverine Buffalo (Bubalus bubalis)
Riverine Buffalo Somatic Cell Count Subclinical Mastitis Indicator Trace Minerals Enzyme Activity
2016/5/9
Mastitis is a highly morbid disease that requires detection at the subclinical stage. Tropical countries like India mainly depend on milch buffaloes for milk. The present study was conducted to invest...