搜索结果: 1-15 共查到“knock-in”相关记录16条 . 查询时间(0.046 秒)
Analysis of prevalence and degree of macrocephaly in patients with germline PTEN mutations and of brain weight in Pten knock-in murine model
: PTEN Hamartoma Tumour syndrome Cowden syndrome
2015/12/21
PTEN Hamartoma Tumour Syndrome (PHTS) includes Cowden syndrome (CS), Bannayan-Riley-Ruvalcaba syndrome (BRRS),
and other conditions resulting from germline mutation of the PTEN tumour suppressor gene...
Fundamental study of detection of muscle hypertrophy-oriented gene doping by myostatin knock down using RNA interference
In vitro and in vivo transformation C2C12 cultured cell
2015/5/11
To investigate the feasibility of developing a method for detection of gene doping in power-athletes, we devised an experimental model system.
Knock-in of Enhanced Green Fluorescent Protein or/and Human Fibroblast Growth Factor 2 Gene into β-Casein Gene Locus in the Porcine Fibroblasts to Produce Therapeutic Protein
Knock-in Homologous Recombination Therapeutic Proteins Porcine β-casein Gene
2016/5/17
Transgenic animals have become important tools for the production of therapeutic proteins in the domestic animal. Production efficiencies of transgenic animals by conventional methods as microinjectio...
Light-weight primitive, feather-weight security? A cryptanalytic knock-out. (Preliminary results)
Light-weight block cipher structural attack
2014/3/12
In [12], the authors present a new light-weight cryptographic primitive which supports an associated RFID-based authentication protocol. The primitive has some structural similarities to AES, but is p...
基于离散小波变换的二甲醚HCCI爆震试验（Experimental Analysis of Knock in a DME HCCI Engine Using Discrete Wavelet Transform）
二甲醚 均质压燃 爆震
2009/5/22
在一台由柴油机改造为二甲醚进气道喷射的发动机上，用离散小波变换分析正常燃烧工况、爆震工况的缸内压力，计算其在各尺度细节部分的能量特征值，研究二甲醚HCCI燃烧的爆震特性。结果表明，正常燃烧工况、爆震工况缸内压力的能量特征值分布具有明显的规律。正常燃烧工况时，细节部分D3的能量特征值最大；爆震工况时，细节部分D1的能量特征值最大。转速升高或进气道喷射燃料添加LPG对正常燃烧工况、爆震工况缸内压力能量...
RNAi-mediated knock down of mammalian selenocysteine lyase
Selenocysteine Selenocysteine lyase Selenoprotein
2009/4/1
Selenocysteine lyase (SCL), which specifically catalyzes the decomposition of L-selenocysteine into Se and L-alanine, is proposed to function as a Se delivery protein to selenophosphate synthetase in ...
Immortalized testis cell lines from estrogen receptor（ER）alpha knock-out and wild-type mice expressing functional ERalpha or ERbeta
Immortalization HPV E6/E7 in vitro models
2008/12/29
The surprising findings that male mice lacking the estrogen receptor (ER) alpha (alphaERKO) have atrophic testis and are infertile proved that ERalpha is involved in normal testicular function. To o...
Epithelial Localization of Green Fluorescent Protein-Positive Cells in Epididymis of the GAD67-GFP Knock-in Mouse
Narrow cell GABA immunohistochemistry GABAA receptor GABAB receptor
2008/12/23
-Aminobutyric acid (GABA), which is a major inhibitory neurotransmitter in the brain, is also found in many peripheral nonneuronal tissues, including male reproductive organs. However, the distrib...
Recent Progress in Biotechnology-based Gene Manipulating Systems to Produce Knock-In/Out Mouse Models
Transgenic Knock In/Out ROSA26 Tetraploid ES Cells Gene Manipulation
2016/4/27
Gene-manipulated mice were discovered for the first time about a quarter century ago. Since then, numerous sophisticated technologies have been developed and applied to answer key questions about the ...
基因敲除是研究生物体基因功能的有效手段。通过基因敲除建立的鼠疾病模型，在研究基因功能及人类疑难病症致病机制等方面发挥着前所未有的作用。本文对目前已获得的基因敲除鼠疾病模型进行了分类和总结，为相关研究的展开奠定了基础。
Red重组系统及在微生物基因敲除中的应用--The Red Recombination System and Its Application to Gene Knock-out in Microorganism
Red重组系统 基因敲除 抗药性基因 Red recombination system gene knock-out resistant gene
2007/12/5
在完成了对各种微生物基因组的测序以后，功能基因学的研究变得尤为重要。研究基因功能最直接的方法便是将待研究的基因失活。最初构建基因突变体是采用大肠杆菌的RecA系统，但是RecA重组系统操作复杂，重组效率低。最近建立了Red重组系统，该系统由3个蛋白组成：α蛋白(即λ核酸外切酶)，β蛋白，Gam蛋白。应用Red系统进行基因敲除，可以直接利用线性打靶DNA，两侧同源臂长度在35~60 bp即可发生同源...
Knock Detection and Analyses with Ionization Sensor and Block Vibration Sensor in SI Engine
2007/7/28
期刊信息
篇名
Knock Detection and Analyses with Ionization Sensor and Block Vibration Sensor in SI Engine
语种
英文
撰写或编译
撰写
作者
?Wu xiaomin,Wang ying,Li Fing
第一作者单位
xi'an jiaotong university
刊物名称
2002 the Fifth...
The mechanism of improving the knock-out properties of moulding sands with water glass
Moulding sands Water glass Knock-out properties New additive Glassex
2011/3/15
The article concerns a trial of explaining the mechanism of improving the knock-out properties of moulding sands with water glass made in ester technology after using the new additive called Glassex. ...
HIGH-TEMPERATURE EXPANSION AND KNOCK-OUT PROPERTIES OF MOULDING SANDS WITH WATER GLASS
Moulding sands Water glass Knock-out properties New additive Glassex
2011/3/10
The article focuses on the topic of improving the knock-out properties of moulding sand with water glass and ester hardener. It is settled that the cause of worse knock-out properties of moulding sand...
13/11/2006，EnBW Ludwigsburg lost for the first time in the German BBL to fall into a three-way tie for first place with Alba Berlin and RheinEnergie Koln, who both rolled to their seventh-straight vic...