搜索结果: 1-15 共查到“leptin”相关记录92条 . 查询时间(0.109 秒)
瘦素(leptin)是一种重要的激素，参与调节动物的摄食、繁殖和能量消耗，其可以通过抑制食欲和促进能量代谢的方式维持机体能量稳态。大多数鱼类具有双重瘦素基因。在本研究中，利用PCR技术克隆了大口黑鲈leptin A基因的编码区，其开放阅读框(ORF)为486 bp，编码161个氨基酸蛋白。通过与其他物种进行同源性比对，发现鲈形目的leptin基因的保守性较高，一致性高达91.46%，在大口黑鲈le...
半滑舌鳎两种leptin基因的体外重组表达和生物活性分析
半滑舌鳎 leptin 原核表达 生物活性
2020/1/16
根据半滑舌鳎lepa和lepb编码氨基酸序列合成开放阅读框ORF肽段。利用原核表达载体pEQ30成功构建了半滑舌鳎lepa/pQE30和lepb/pQE30重组质粒，分别转化至大肠杆菌M15后，经IPTG诱导获得了N端含6个组氨酸的半滑舌鳎LepA和LepB重组蛋白。获得的重组蛋白大小均为16 ku，37 °C下用0.5 mmol/L的IPTG诱导4 h后目的蛋白表达量最高，主要以包涵体形式存在。...
Alterations in human milk leptin and insulin are associated with early changes in the infant intestinal microbiome
milk leptin insulin the infant intestinal microbiome
2018/11/12
We read with great interest the study by Lemas et al. (1) that reported early changes in the gut microbiota composition and functions of exclusively breastfed infants born from obese mothers compared ...
Leptin concentrations in the United States: relations with demographic and anthropometric measures
Leptin anthropometry ethnicity
2016/6/14
Leptin is a peptide that is strongly correlated
with adiposity and is a potential determinant of obesity and its
complications.
Since first reported less than a decade ago (1), leptin has been a
topic of considerable study. The variation in serum or plasma leptin
concentrations has been described according to sex, age, measu...
Effect of long-term changes in diet and exercise on plasma leptin concentrations
Leptin diet exercise
2016/6/12
Although it is known that plasma leptin concentrations
correlate with the amount of adipose tissue in the body,
little information is available on the long-term effects on leptin
concentrations of ...
Effect of prolonged moderate and severe energy restriction and refeeding on plasma leptin concentrations in obese women
OB gene obesity leptin
2016/6/1
Plasma leptin in humans is subject to both longand
short-term regulation; it correlates with indexes of body fat
that can only change slowly. However, short-term fasting causes
large and rapid decr...
Mechanisms regulating leptin production: implications for control of energy balance
energy balance leptin
2016/6/1
During the past 2 y the leptin field has continued to expand rapidly (from 600 to >2000 citations currently in the MEDLINE database), extending leptin biology into areas well beyond feeding behavior a...
Plasma leptin concentrations in obese children: changes during 4-mo periods with and without physical training
exercise obesity children
2016/5/30
Little is known about the effects of physical
training on plasma leptin concentrations in children.
Leptin is known to be cleared by the kidney, a tissue
with substantial leptin receptor mRNA expression; however,
lung, liver, and muscle tissues also express leptin receptor messenger
RNA and it is...
Study of Serum Levels of Leptin, C-Reactive Protein and Nutritional Status in Hemodialysis Patients
Serum Leptin CRP Hemodialysis Patients Nutritional Status
2015/11/9
Background: Leptin is secreted by adipose tissue and decreases appetite. However, the role of leptin in the pathogenesis of hemodialysis (HD)-related malnutrition has not been fully evaluated.
Missense mutations in exon 2 of the porcine leptin receptor gene and their associations with litter size and body weight
LEPR SNPs pigs
2015/6/8
Leptin receptor (LEPR) gene is regarded as a “candidate-gene” of production traits. The aims of this study were to detect polymorphisms of exon 2 within LEPR gene and to investigate their associations...
The Effects of Exercise on Food Intake and Hunger: Relationship with Acylated Ghrelin and Leptin
Energy intake energy expenditure exercise hunger acylated ghrelin weight loss appetite
2015/5/7
This study investigated the effects of a long bout of aerobic exercise on hunger and energy intake and circulating levels of leptin and acylated ghrelin. Ten healthy male subjects undertook two, 4 h t...
Effect of Energy Expenditure and Training Status on Leptin Response to Sub-Maximal Cycling
Hormones anaerobic training acute exercise
2015/4/22
We examined the leptin response and related hormones during and after two sub-maximal exercise protocols in trained and untrained subjects. During this study, plasma concentrations of leptin [Lep], in...
Leptin, its Implication in Physical Exercise and Training: A Short Review
Leptin exercise training hormones
2015/3/18
Leptin, a hormone synthesized by fat tissue had been noted to regulate energy balance and metabolism and thus to influence body weight. The influence of acute exercise and chronic exercise training on...