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Coenzyme Q10 prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth
developmental programming liver disease coenzyme Q low birth weight accelerated postnatal growth
2018/11/28
Background: It is well established that low birth weight and accelerated postnatal growth increase the risk of liver dysfunction in later life. However, molecular mechanisms underlying such developmen...
TRAF-interacting protein, an inhibitor of the canonical nuclear factor-kappaB pathway, plays a key role in the estradiol -dependent apoptosis of the dual-phenotype gamma amino butyric acid/glutamate neurons in the anteroventral periventricular nucleus of the male rat
Mediated estradiol LH surge neurons male AVPV E2 - mediated cell death neurons
2014/12/11
The anteroventral periventricular nucleus (AVPV) of the preoptic area mediates the positive feedback effects of estradiol (E2) on LH surge in rats. Consistent with their role in female reproduction, t...
Oxidative Stress and Oxidative Damage in Male Rat Erythrocytes Associated with Prolonged Exposure to Smoke Pollution
Lipoperoxidation Antioxidants Oxidative Stress Antioxidases Smoke Pollution Oxidative Damage Erythrocytes
2013/3/11
Exposure of animals to different duration of smoke can result in a wide range of adverse clinical conditions. Toxicological consequences arising from prolonged exposure may not be totally enumerated. ...
Feeding Effect of an Anabolic Steroid, Nandrolone, on the Male Rat Testis
Nandrolone Testis Steroidogenic Enzymes Testosterone Fertility
2016/5/5
Nandrolone, 19-nortestosterone, is a synthetic androgenic-anabolic steroid promoting muscle growth. Nandrolone is also present in pig meat and sera at non-negligible levels. A number of scientific rep...
Luteinizing hormone secretion by male rat pituitary cells perifused in vitro：effect of experimental left varicocele and orchiectomy
Luteinizing hormone secretion male rat pituitary cells
2009/2/23
It has been shown previously that experimental left varicocele in the rat, results in a bilateral decrease in intratesticular testosterone. In the present work, pituitary responsiveness to GnRH as a...
Cyclophosphamide in the male rat：new pattern of anomalies in the third generation
Cyclophosphamide male rat anomalies third generation
2009/2/23
Several abnormalities, such as postnatal deaths and behavioral impairments, have been previously reported in the progeny of male rats exposed to the cytostatic drug cyclophosphamide 60 days prior to...
Pituitary response to LHRH during chronic renal insufficiency in the male rat
Pituitary LHRH chronic renal insufficiency male rat
2009/2/23
Chronic renal insufficiency was induced in young adult male rats by a 2-step 5/6 nephrectomy. Four weeks after surgery the rats were anesthetized with ketamine and injected with saline or 1, 5, 10...
Testosterone dose-dependency of sexual and nonsexual behaviors in the gonadotropin-releasing hormone antagonist-treated male rat
Testosterone dose-dependency sexual nonsexual behaviors gonadotropin-releasing hormone male rat
2009/2/23
The testosterone dose-dependency of several mating and nonmating behaviors was examined in the male rat, chemically castrated with a GnRH antagonist analog. Graded doses of testosterone enanthate ...
Antimitotic drugs in the male rat. Behavioral abnormalities in the second generation
Antimitotic drugs male rat Behavioral abnormalities second generation
2009/2/23
The second generation descended from rats treated either with cyclophosphamide alone or with both cyclophosphamide and vinblastine were investigated. As in the first generation, the offspring were...
Antimitotic drugs（cyclophosphamide and vinblastine）in the male rat. Deaths and behavioral abnormalities in the offspring
cyclophosphamide vinblastine male rat spermatogonia mutation offspring
2009/2/23
The spermatogenesis and the offspring of male rats treated either with cyclophosphamide alone, or with both cyclophosphamide and vinblastine were investigated. The offspring were evaluated for the...
Recovery of gonadal functions in the adult male rat following cessation of five-month daily treatment with an LHRH agonist
LHRH agonist testicular steroidogenesis ventral prostate seminal vesicles spermatogenesis
2009/2/20
This study describes the recovery of various parameters of the pituitary-gonadal axis following five months of daily treatment of adult male rats with a potent LHRH (luteinizing hormone-releasing ...
Influence of estradiol on accessory reproductive organs in the castrated male rat. Effects of bromocriptine and flutamide
estradiol accessory reproductive organs castrated male rat
2009/2/19
Estradiol partially maintained the weights of the dorsolateral prostate and seminal vesicles in castrated adult male rats. One group of animals received subcutaneous injections of estradiol (0.01 ...
Prolactin Stimulation of Testicular Steroid Biosynthesis in the Male Rat
prolactin LHRH 17-hydroxylase desensitization steroidogenesis LH receptor prolactin receptor
2009/2/19
The effect of prolactin on testicular steroidogenesis was studied in intact adult male rats and in animals treated for 12 days with the LHRH-agonist [D-Ala6, des-Gly-NH210]LHRH ethylamide (LHRH-agon...
Temporal relation between leptin and various indices of sexual maturation in the male rat
Puberty adipose tissue testosterone gonadotropins
2009/2/18
Recent studies in humans and rhesus monkeys have suggested the possibility that the adipose tissue hormone leptin has a stimulatory and/or permissive effect on the onset of puberty in the male. We...
Inhibin B levels in plasma of the male rat from birth to adulthood：effect of experimental manipulation of Sertoli cell number
Inhibin B levels male rat experimental manipulation Sertoli cell number
2009/2/18
Sertoli cells undergo important changes in their number and function at different ages in the rat and may be the primary source of circulating inhibin B. The aims of this study were 1) to establis...