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苦皮藤根皮的1HNMR指纹图解析
苦皮藤 1HNMR指纹图 angulatin C
2010/1/14
目的对苦皮藤的1HNMR指纹图进行解析.方法用硅胶柱色谱法分离苦皮藤根皮CGEA的化学成分,鉴定单体化合物的结构并对其进行1HNMR研究,从而实现苦皮藤根皮的1HNMR指纹图解析.结果不同来源的苦皮藤样品,其1HNMR指纹图有很好的重现性和高度的特征性.从其CGEA中分得3个主要成分,经光谱分析鉴定其结构,分别为:angulatinA(1),angulatinB(2)和angulatinC(3)....
AFLP法构建人参、西洋参基因组DNA指纹图谱
人参 西洋参 引种西洋参 基因组DNA 扩增片段长度多态性DNA DNA指纹图谱
2010/1/14
目的 采用扩增片段长度多态性DNA(AFLP)分子遗传标志技术，分析人参、西洋参基因组DNA多态性。方法 人参、西洋参干燥根基因组DNA，经EcoRI/MseI酶切并与其相应的人工接头连接后，使用选择性引物进行PCR扩增。结果 经变性聚丙烯酰胺凝胶电泳检测，成功构建出多态性丰富和重复性好的人参、西洋参DNA指纹图谱。结论 AFLP法有望成为一种独立的切实可行的手段，将在人参、西洋参等药用植物的鉴定...
目的：观察异丹叶大黄素和白藜芦醇对分别由炎性三肽(fMLP)和钙离子载体A23187(A23187)诱导的小鼠腹腔巨噬细胞白细胞介素6(interleukin 6, IL-6) mRNA表达水平的影响。方法：用半定量mRNA的RT-PCR。结果：异丹叶大黄素和白藜芦醇在2×10-6和2×10-5 mol.L-1浓度下，均能抑制fMLP和A23187诱导的小鼠腹腔巨噬细胞IL-6 mRNA的表达。结...
中国不同地区蛇床的rDNA ITS序列分析
蛇床 rDNA内转录间隔区 纬度
2010/1/12
目的：探讨不同分布区的蛇床Cnidium monnieri的ITS序列变异与其地理分布和化学成分的相关性。方法：设计2对引物，Pf+Pb及P5.8S ITS1+P5.8S ITS2，PCR扩增产物纯化后用银染法或ABI 310测序。结果：得到核糖体DNA中的ITS及5.8S rDNA完全序列，18S和26S rDNA部分序列,共约700 bp。5个地点样品的ITS-1及ITS-2的序列大小分别为2...
目的：研究中国汉族人群S-美芬妥英4'-羟化代谢遗传多态性。方法：以美芬妥英为探针药物采用手性毛细管气相色谱法测定尿中S-/R-MP浓度比值， 对90名志愿者进行了表型分型测定，应用PCR技术对其中的26名志愿者进行了S-美芬妥英4'-羟化酶（CYP2C19）基因分析。结果：表型分析结果，11人属慢代谢者（PM），S/R比值0.95；基因分析结果，6人为野生型纯合子（wt/wt）；10人为杂合子...
Blood samples (291857) from 24 provinces of Iran were tested for ABO and Rh groups. The Rh complexes as well as Kell, Duffy, Kidd, Lutheran, Kp and Xg blood groups were tested only on a part of the ma...
Background: While the results of genetic research have increased our medical knowledge, promoted health and treatment of illness, some unique ethical problems arise about this type of research. Geneti...
STUDY OF SEX,AGE AND BLOOD GROUPS (ABO,Rh) DISTRIBUTIONS IN THALASSEM IA PATIENTS IN IRAN
SEX AGE AND BLOOD GROUPS DISTRIBUTIONS THALASSEM PATIENTS IRAN
2009/12/31
Thalassemias, because of climatic, geographic and ecological conditions, are the most common among the genetically endemic in Iran, especially m provinces adjacent to the Caspian Sea and the Persian G...
COMPARATIVE STUDIES OF THE CHROMOSOMAL ARRANGEMENT IN THE C-METAPHASE BETWEEN NORMAL KARYOTYPE AND TRISOMY-21
Chromosomal arrangements C-metaphase Radial & Homologue distances (+21) Satellite-association
2009/12/31
Human chromosomes in amnion cells and lymphocytes with normal karyotype and in lymphocytes with pathological karyotype (2n=47, +21) were compared as to their position in the metaphase. None of the col...
DNA-Harmalol interaction: The effects of Harmalol on the solution structure of calf-thymus DNA studied by FTIR spectroscopy
Calf-thymus DNA Harmalol FTIR
2009/12/31
The interaction of hamalol with calf-thymus DNA was investigated at physiological pH with drug/DNA (phosphate) molar ratio(r) of 1/40. Fourier transform infrared difference spectroscopy were used to e...
To study the changes of serum uric acid level which is influenced by various factors including nutrition, race, socio-economic conditions age, sex, obesity and hyper lipidemia, a wide variety of surve...
Preliminary Report: EVIDENCE OF AUTOSOMAL RECESSIVE FORM OF ALPORT SYNDROME IN IRAN
Alport syndrorme Hereditary nephritis IRAN
2009/12/30
Alport syndrome is a progressive hereditary nephritis leading to renal failure. Nearly all of the documents declare that Alport syndrome is inherited as X-linked dominant trait and reports of autosoma...
CONSANGUINITY IN IRAN
Moslems Zoroastrians Jews
2009/12/30
A total of 8641 married couples were investigated from 28 Iranian populations for consanguineous marriages and coefficient of inbreeding. The results showed considerable differences in the rate and ki...
KNOWLEDGE OF MEDICAL GENETICS OF A GROUP OF PHYSICIANS,A PRELIMINARY STUDY
Medical genetic GENETICS PHYSICIANS
2009/12/30
In a preliminary study, descriptive cross sectional, knowledge of 550 general practitioners, pediatrics and gynecology residents were evaluated in relation to medical genetics. A questionnaire was dev...
A REPORT OF 4 CASES OF CHROMOSOME ABNORMALITIES IN 115 FAMILIES WITH CONSANGUINEOUS MARRIAGE
Chromosome study Genetic counseling
2009/12/30
115 couples with consanguineous marriage, who had experienced reported abortions or still births either in their close relatives (3 couples) or themselves (1 couple) were exposed to genetic counseling...