搜索结果: 61-75 共查到“知识库 口腔组织学与口腔病理学”相关记录803条 . 查询时间(3.704 秒)
不同代次诱导多能干细胞增殖及牙周定向分化的能力
多能干细胞 细胞代次 牙周定向分化 细胞增殖
2018/12/3
目的： 研究不同代次诱导多能干细胞（induced pluripotent stem cells，iPSCs）在增殖及向牙周定向分化能力上的区别，为今后深入研究和可能的临床应用提供理论基础。方法：复苏不同代次（P5、P10、P15、P20）人牙龈成纤维细胞来源的iPSCs，观察细胞形态并比较其增殖能力,进一步将各代次细胞形成拟胚体，于含生长分化因子-5（growth/differentiation...
目的：研究氧化锌丁香油类（zinc oxide and eugenol based sealers，ZOE）、环氧树脂类（epoxy resin sealers，ERS）、硅酮基类(silicone based sealers，SBS)根管封闭剂对牙周膜细胞(human periodontal ligmant cells, hPDLCs)的增殖和矿化潜能的影响。方法：选用3颗不同人牙齿来源的hPD...
目的：使用图像分析软件对牙菌斑染色图像进行分析，验证该技术的可操作性和实用性，考察该方法的可重复性，并评价不同菌斑染色方式对结果的影响。方法：从北京大学医学部口腔医学专业新入校学生中招募符合纳入标准的志愿者30人，菌斑染色后拍摄标准化口内前牙区数字图像，用Image Pro Plus 7.0软件进行图像分析，同时评价前牙区的Quigley-Hein菌斑指数。
骨性安氏Ⅲ类手术患者前牙区的牙槽骨厚度
错牙合 安氏Ⅲ类 测颅法 牙槽骨质吸收
2018/11/29
目的：研究正畸正颌联合治疗的骨性Ⅲ类错牙合患者上、下颌前牙牙槽骨厚度的特征。方法：选取2011年11月至2015年1月于北京大学口腔医院进行正畸正颌联合治疗的54名成人骨性Ⅲ类错牙合患者，摄取治疗前头颅侧位片，利用单样本t检验方法与北京大学正常牙合样本库的相应数值进行比较，获取其牙槽厚度的特征,对样本病例的矢状向及垂直向骨性测量值与上、下颌前牙牙槽骨厚度采用Pearson相关性分析。根据颌骨矢状向...
目的：比较口腔鳞状细胞癌（oral squamous cell carcinoma, OSCC）发展过程中各阶段病损的人类乳头瘤病毒（human papilloma virus, HPV）感染率，以探讨将HPV感染作为癌变预测信号的可能性，同时比较两种方法在检测口腔内HPV感染方面的灵敏度差异。方法：使用第二代杂交捕获（hybrid capture，HC-Ⅱ）法检测255例口腔黏膜上皮细胞样本中的...
目的：探讨0.2 mm咬合干扰不同时间点去除与大鼠咀嚼肌机械痛觉敏感恢复的关系。方法： 选用雄性Sprague-Dawley大鼠（200~220 g），通过在大鼠右上第一磨牙粘固0.2 mm厚金属冠建立咬合干扰模型。实验随机分为对照组（包括空白对照组和假干扰组）和实验组（包括咬合干扰组和2、3、4、5、6 d咬合干扰去除组）， 共8组，每组5只大鼠，分别于建模前1、2、3 d及建模后1、3、5、7...
目的：明确口腔鳞癌组织和细胞中黏液素样细胞表面黏附分子CD24的表达模式、作用及其作为治疗靶点的潜在价值。方法：利用免疫组化、real-time RT-PCR和Western blot方法，明确CD24在78例人口腔组织标本和59例动物模型金地鼠（Hamster buccal）颊囊组织标本，以及口腔癌前病变上皮细胞DOK4、口腔鳞癌细胞CAL-27和WSU-HN6中的表达模式；以CAL-27和WS...
Jaw Intraosseous Lesions Biopsied Extracted From 1998 to 2010 in an Iranian Population
Jaw Population Prevalence
2015/11/6
Background: Jaw bones might be potential locations for different lesions. Differences in prevalence and the type of lesions can help in designing and programming prevention procedures in health care c...
Is there a "safety zone" in the mandibular premolar region where damage to the mental nerve can be avoided if periapical extrusion occurs?
Inferior Alveolar Nerve Paresthesia Foramen
2015/7/16
The mandibular premolars are located close to the mental foramina (Fig. 1). As such, various events affecting these teeth, such as odontogenic infection1 and orthodontic, endodontic, periodontal or su...
Reconstruction of temporomandibular joint ankylosis with temporalis myofascial flap in a cat: a case report
condylectomy interpositional arthroplasty ankylotic block
2015/3/17
An approximately 7-year-old 1.7kg, female Siamese cat with a history of a malocclusion and an
inability to open its mouth was referred the Animal Medical Center, Chonbuk National University. The cat...
Dynamin and PTP-PEST cooperatively regulate Pyk2 dephosphorylation in osteoclasts
signaling Tyrosine kinase Osteoclasts
2014/11/6
Bone loss is caused by the dysregulated activity of osteoclasts which degrade the extracellular bone matrix. The tyrosine kinase Pyk2 is highly expressed in osteoclasts, and mice lacking Pyk2 exhibit ...
Nmp4/CIZ suppresses the response of bone to anabolic parathyroid hormone by regulating both osteoblasts and osteoclasts
c-fos Fra-2 osteoclastogenesis
2014/11/6
How parathyroid hormone (PTH) increases bone mass is unclear, but understanding this phenomenon is significant to the improvement of osteoporosis therapy. Nmp4/CIZ is a nucleocytoplasmic shuttling tra...
Cell adhesion to the extracellular matrix (ECM) is essential for cell migration, proliferation, and embryonic development. Cells can contact the ECM through a wide range of matrix contact structures s...
Susceptibility of methacrylate-based root canal filling to degradation by bacteria found in endodontic infections
clear zone degradation endodontic bacteria Resilon
2014/11/6
Objectives: To present a case of endodontic failure obturated with a methacrylate-based root filling material, Resilon/ RealSeal (RS). To determine if RS is susceptible to biodegradation by endodontic...
Proteomic profiling of salivary gland after nonviral gene transfer mediated by conventional plasmids and minicircles
drug development toxicology translational research
2014/11/6
In this study, we compared gene transfer efficiency and host response to ultrasound-assisted, nonviral gene transfer with a conventional plasmid and a minicircle vector in the submandibular salivary g...