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“为躲避花粉，送孩子去哪儿上学？”，协和专家告诉你……
花粉 变态反应 过敏性结膜炎
2024/4/15
“为躲避花粉，送孩子去哪儿上学最佳？”最近又到了“过敏季”，北京协和医院变态反应科主任医师尹佳在门诊时遇到有过敏患者的家长向自己征求意见。
免疫细胞里藏着“过敏记忆”
免疫细胞 过敏记忆 变态反应
2024/4/9
“全身甚至脸上随时随地出现大片的红肿、瘙痒，感觉自己生活得已经非常仔细了，每天打扫卫生，衣物勤洗勤换，不知道为什么还会过敏，而且越来越严重。”每到春天，家住马鞍山市的张女士就苦不堪言。
氢气改善冠状动脉旁路移植术患者血中氧化应激和炎症因子水平
氢气 体外循环 炎症反应 氧化应激
2020/6/8
观察氢气对CPB下冠状动脉旁路移植术患者血中氧化应激及炎症反应的调控作用，为CPB术中心肌保护提供新的方法。 方法 选取择期全身麻醉下行CPB冠状动脉旁路移植术患者30例，采用随机数字表法分为两组：氢气组和对照组，每组15例。氢气组在CPB开始时给予2%氢气联合氧气转机1 h，对照组只给予氧气。在麻醉诱导后切皮前（T0）、CPB开始5 min（T1）、CPB结束时（T2）、术后4 h（T3）、术后...
克林霉素磷酸酯与地塞米松配伍静脉滴注致变态反应3例
克林霉素磷酸酯 地塞米松配伍 静脉滴注 变态反应
2013/10/31
探讨克林霉素磷酸酯注射液与地塞米松注射液配伍的合理性。方法门诊使用克林霉素磷酸酯注射液的患者50例，采用3种方法给药：①克林霉素磷酸酯注射液常规剂量1.2 g加地塞米松注射液10 mg配伍静脉滴注， qd；②克林霉素磷酸酯注射液1.2 g和地塞米松注射液10 mg分组静脉滴注， qd；③使用单组克林霉素注射液1.2 g静脉滴注， qd。结果克林霉素磷酸酯注射液和地塞米松注射液配伍应用时有3例发生变...
Evaluation of Novel Scoring System Named 5-5-5 Exacerbation Grading Scale for Allergic Conjunctivitis Disease
allergic conjunctivitis atopic keratoconjunctivitis clinical severity score vernal keratoconjunctivitis
2010/11/16
The median severity scores of the 5-5-5 exacerbation grading scale in VKC, AKC and AC were 243 (range: 12-444), 32.5 (11-344), and 13 (2-33), respectively. The severity score of each ACD disease type ...
Clinical Evaluation of Total IgE in Tears of Patients with Allergic Conjunctivitis Disease Using a Novel Application of the Immunochromatography Method
allergic conjunctivitis disease immunochromatography immunoglobulin E
2010/11/16
The positive ratio obtained by this novel application of the immunochromatography assay was 38 of the 41 in the patients with ACD and none in the 7 controls. IgE indices for the VKC group, AKC group a...
Evaluation of Molecular Basis of Cross Reactivity between Rye and Bermuda Grass Pollen Allergens
Bermuda grass cross reactivity immunoblot inhibition rye grass SDS-PAGE
2010/11/16
Our data suggests that a possible explanation for the limited cross reactivity between the Pooids and Chloridoids may, in part, be due to the absence of group 5 allergen from Chloridoid grasses. This ...
Hev b 6.02 Is the Most Important Allergen in Health Care Workers Sensitized Occupationally by Natural Rubber Latex Gloves
allergen health care workers latex allergy latex gloves skin prick test
2010/11/16
Background: Natural rubber latex (NRL) allergy is a common occupational disease in health care workers (HCW). However, few reports have compared the major allergen of HCWs to those in gloves that are ...
Depletion of Thymus-Derived CD4+CD25+ T Cells Abrogates the Suppressive Effects of α-galactosylceramide Treatment on Experimental Allergic Conjunctivitis
allergic conjunctivitis eosinophils regulatory T cells thymus α-galactosylceramide
2010/11/17
α-GalCer treatment significantly suppressed EC in the thymus-intact mice that had not been treated with anti-CD25 Ab. In contrast, α-GalCer treatment of thymectomized and anti-CD25 Ab-treated mice did...
Targeting Human Mast Cells Expressing G-Protein-Coupled Receptors in Allergic Diseases
allergic diseases bronchial asthma GPCRs human mast cells urticaria
2010/11/17
The G-protein-coupled receptors (GPCRs) are the largest known group of integral membrane receptor proteins and are the most common targets of pharmacotherapy. Mast cells (MCs) have been reported to pl...
IgE Profiles of Bermuda Grass Pollen Sensitised Patients Evaluated by Phleum Pratense Allergens Phl P 1, 2, 4, 5, 6 , 7, 11, 12
Bermuda grass recombinant allergens timothy grass
2010/11/17
Our data show that all BGP-allergic patients simultaneously exhibit higher IgE antibody levels to recombinant and natural P. pratense allergens as well as to crude TGP extract. This suggests that when...
Food-Dependent Exercise-Induced Anaphylaxis Induced by Low Dose Aspirin Therapy
cap-system fluorescent enzyme immunoassay food-dependent exercise-induced anaphylaxis low dose aspirin ω-5 gliadin
2010/11/17
Background: Food-dependent exercise-induced anaphylaxis (FDEIA) is a distinct form of common food allergy characteristically induced by a combination of causative food ingestion and physical exercise....
Detection of Specific IgE Antibodies in Sera of Japanese Birch-Allergic Patients Using Recombinant Allergens Bet v 1, Bet v 2 and Bet v 4
Bet v 1 Bet v 2 birch pollinosis RAST
2010/11/17
Background: Birch pollen is the major allergen in pollinosis in northern Japan. IgE reactivity to individual birch pollen allergens has been shown to differ between populations of birch pollen-allergi...
Three Cases of Ortho-phthalaldehyde-induced Anaphylaxis after Laryngoscopy: Detection of Specific IgE in Serum
basophils ELISA histamine release IgE-mediated anaphylaxis skin test
2010/11/18
Background: Ortho-phthalaldehyde (OPA) has recently been used as a disinfectant for various medical apparatuses. OPA is not generally recognized as a potential allergen.
Case Summary: Subsequent to o...