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Rice U. Biologists Create Toolkit For Tuning Genetic Circuits(图)
Rice U. Biologists Create Toolkit Tuning Genetic Circuits
2018/2/1
Rice University scientists have created a toolkit for synthetic biologists who need to precisely tune the input and output levels of genetic circuits.The research, which is online in Nature Communicat...
Genetic relationship between type traits, number of lactations initiated, and lifetime milk performance in Czech Fleckvieh cattle
dairy cows longevity lifetime performance conformation traits
2017/12/25
Genetic relationship was analyzed between type traits and longevity measures in dual-purpose cattle. Data from 91 486 Czech Fleckvieh cows first calved between 2003 and 2009 were used. Longevity was d...
Why might the finding of a new genetic association with inflammatory bowel disease be of potential value in disease control?
new genetic association inflammatory bowel disease potential value disease control
2018/11/20
Inflammatory bowel disease (IBD) has long been recognized as an exaggerated inflammatory response to common antigenic stimuli in the gut. Ulcerative colitis (UC) (1) and Crohn disease (CD) (2) are the...
Ethnic and genetic factors of iron status in women of reproductive age
breastfeeding ethnicity genetic factors hemochromatosis iron overload iron status pregnancy women of reproductive age
2018/11/21
Background: African Americans are at increased risk of iron deficiency (ID) but also have higher serum ferritin (SF) concentrations than those of the general population. The Hemochromatosis and Iron O...
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Genomics Discovery Paves Way For Possible New Treatments Of Genetic Disorders,Diseases
Genomics Paves Way New Treatments Genetic Disorders Diseases
2017/10/24
NSF-funded researchers studying how a bacterium's immune system fights off viruses uncovered a powerful new gene-editing technique called CRISPR-Cas9.CRISPR-Cas9 acts like a pair of molecular-sized sc...
Mediation and modification of genetic susceptibility to obesity by eating behaviors
eating behavior genetic risk score genetics obesity BMI body mass index dieting
2018/11/19
Background: Many genetic variants show highly robust associations with body mass index (BMI). However, the mechanisms through which genetic susceptibility to obesity operates are not well understood. ...
Association of TCN2 rs1801198 c.776G>C polymorphism with markers of one-carbon metabolism and related diseases: a systematic review and meta-analysis of genetic association studies
cobalamin c.776G>C genetic association studies
2018/11/20
Background: Vitamin B-12 (cobalamin) deficiency may produce severe neurologic and hematologic manifestations. Approximately 20–25% of circulating cobalamin binds to transcobalamin 2 (TCN2), which is r...
Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts
BMI adults genetics twins international comparisons
2018/11/15
Background: Genes and the environment contribute to variation in adult body mass index [BMI (in kg/m2)], but factors modifying these variance components are poorly understood.
Genetic mutation trade-offs lead to parallel evolution
Genetic mutation trade-offs parallel evolution
2017/7/20
Organisms in nature adapt and evolve in complex environments. For example, when subjected to changes in nutrients, antibiotics, and predation, microbes in the wild face the challenge of adapting multi...
Insects resist genetic methods to control disease spread,Indiana University study finds
Insects resist genetic methods control disease spread Indiana University
2017/7/20
Researchers are exploring the use of the revolutionary gene-editing tool CRISPR-Cas9 to fight human disease and agricultural blight. But a study from Indiana University has found several challenges to...
Genetic relationship between type traits, number of lactations initiated, and lifetime milk performance in Czech Fleckvieh cattle
dairy cows longevity lifetime performance conformation traits genetic correlation
2018/3/5
Genetic relationship was analyzed between type traits and longevity measures in dual-purpose cattle. Data from 91 486 Czech Fleckvieh cows first calved between 2003 and 2009 were used. Longevity was d...
Sleep characteristics modify the association of genetic predisposition with obesity and anthropometric measurements in 119,679 UK Biobank participants
obesity sleep chronotype nap shift work night-shift workers genetic risk score genes
2018/11/13
Background: Obesity is a multifactorial condition influenced by genetics, lifestyle, and environment.
The influence of genetic susceptibility and calcium plus vitamin D supplementation on fracture risk
fracture bone mineral density genetic risk score calcium vitamin D postmenopausal women
2018/11/13
Background: Fracture is a complex trait, affected by both genetic and environmental factors. A meta-analysis of genome-wide association studies (GWASs) identified multiple bone mineral density (BMD) a...
Scientists develop genetic path to tastier tomatoes
Scientists genetic path tastier tomatoes
2017/2/16
Some consumers crave tastier tomatoes than those available at the supermarket. Now, scientists at the University of Florida Institute of Food and Agricultural Sciences (UF/IFAS) and their partners hav...
New genetic engineering technique could help design,study biological systems
New genetic engineering technique design study biological systems
2017/2/16
A new technique will help biologists tinker with genes, whether the goal is to turn cells into tiny factories churning out medicines, modify crops to grow with limited water or study the effects of a ...