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Researchers Use DNA‘Clews’to Shuttle CRISPR-Cas9 Gene-Editing Tool into Cells
Researchers DNA Clews Shuttle CRISPR-Cas9 Gene-Editing Tool
2015/9/8
CRISPR–Cas9 represents a promising platform for genome editing, yet means for its safe and efficient delivery remain to be fully realized. A novel vehicle that simultaneously delivers the Cas9 protein...
Shell analysis of elliptical guard cells in higher plants: a review
Shell analysis elliptical guard cells higher plants
2015/8/27
This presentation reviews finite element shell analyses (linear and nonlinear, isotropic and anisotropic) of microscopic stomata modeled as doubly-elliptic toroidal shells. Stomata are the regulating ...
Hippocampal Place Cells,Context,and Episodic Memory
hippocampus context discrimination learning spatial
2015/8/7
Although most observers agree that the hippocampus has a critical role in learning and memory, there remains considerable debate about the precise functional contribution of the hippocampus to these p...
Regional distribution of the prostaglandin E2 receptor EP1 in the rat brain: accumulation in Purkinje cells of the cerebellum
prostaglandin E2 EP1 prostanoid receptors rat brain cerebellum Purkinje cells cyclooxygenase neuroimmunology
2015/8/3
Prostaglandin E2 (PGE2), is a major prostanoid produced by the activity of cyclooxygenases (COX) in response to various physiological and pathological stimuli. PGE2 exerts its effects by activating fo...
Protein Classification By Analysis of confocal Microscopic Images of Single Cells
image analysis feature selection classification
2015/7/14
Proteins being present in a living cell fulfil a certain task in the cell. As a consequence of its functionality a protein is located in
certain parts of the cell. If it is made visible the resulting...
UW team programs solitary yeast cells to say ‘hello’ to one another（图）
UW team programs solitary yeast cells hello
2015/7/13
For centuries, humans have been playing with yeast. But these simple fungal cells usually do their jobs — making bread rise or converting sugar into alcohol — without having to communicate or work tog...
Innate defense capability of challenged primary bovine mammary epithelial cells after an induced negative energy balance in vivo
pbMEC mastitis energy deficit E. coli
2015/6/23
Negative energy balance (NEB), if followed by metabolic imbalance, is a common problem in
high-yielding dairy cows frequently associated with inflammation of the mammary gland. After entering the
...
There aren’t any giants or midgets when it comes to the cells in your body, and now Duke University scientists think they know why.A new study appearing June 3 in Nature shows that a cell’s initial si...
Many living things can respond to electric fields, either moving or using them to detect prey or enemies. Weak electric fields may be important growth and development, and in wound healing: it’s known...
Scientists pinpoint genes that make stem cells in plants,revealing origin of beefsteak tomatoes（图）
Scientists stem cells in plants origin of beefsteak tomatoes
2015/6/2
A team of scientists at Cold Spring Harbor Laboratory (CSHL) has identified a set of genes that control stem cell production in tomato. Mutations in these genes explain the origin of mammoth beefsteak...
Derivation of endothelial colony forming cells from human cord blood and embryonic stem cells
Embryonic Stem Cells Directed Differentiation Human Umbilical Cord Blood
2015/5/25
Endothelial Colony Forming Cells (ECFCs) are highly proliferative endothelial progenitor cells with clonal proliferative potential and in vivo vessel forming ability. While endothelial cells have been...
Myeloid cells induce neurofibromatosis type 1 aneurysm formation through inflammation and oxidative stress
Oxidative Stress cre/lox Murine Model Aneurysm
2015/5/25
Neurofibromatosis Type 1 (NF1) is a genetic disorder resulting from mutations in the NF1 tumor suppressor gene. Neurofibromin is the protein product of NF1 and functions as a negative regulator of Ras...
Lymph node and peri-lymph node stroma : phenotype and interaction with T-cells
Ly51 iNOS IDO1
2015/5/21
The non-hematopoietic, stationary stromal cells located inside and surrounding skin-draining lymph nodes play a key role in regulating immune responses. We studied distinct populations of lymph node s...
Neurexophilin1 suppresses the proliferation of hematopoietic progenitor cells
Neurexophilin Dystroglycan Hematopoiesis Hematopoietic niche
2015/5/21
Neurexin I alpha (NRXN1α) and Dystroglycan (DAG1) are membrane receptors which serve as mutual ligands in the neuronal system. Neurexophilins (NXPHs) bind NRXN1α. Both NRXN1α and DAG1 were expressed i...
Characterization of Bovine NANOG5′-flanking Region during Differentiation of Mouse Embryonic Stem Cells
Bovine Embryonic Stem Cell NANOG Promoter Neural Differentiation Adipocyte Differentiation
2016/5/19
Embryonic stem cells (ESCs) have been used as a powerful tool for research including gene manipulated animal models and the study of developmental gene regulation. Among the critical regulatory factor...