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The antifertility effect of triptolide and other related compounds, isolated from Tripterygium wilfordii, has been demonstrated in male rats. The exact sites and mechanism of action of triptolide ...
Sperm motion predicts fertility in male hamsters treated with alpha-chlorohydrin
Sperm motion predicts fertility male hamsters alpha-chlorohydrin
2009/2/17
An understanding of the relationship between altered sperm motion and sperm function (fertility) is important when interpreting the biological significance of toxicant-induced changes in sperm veloc...
Hst7：a male sterility mutation perturbing sperm motility, flagellar assembly, and mitochondrial sheath differentiation
Allele asthenospermia axoneme t complex t haplotype
2009/2/17
Hst7, a mouse hybrid sterility locus, has been mapped in close linkage to four other hybrid sterility loci, on proximal chromosome 17 within the t complex. When an allele (s) of Hst7 from the specie...
Estrogen receptor（alpha and beta）expression in the excurrent ducts of the adult male rat reproductive tract
Efferent ductules immunohistochemistry
2009/2/17
The understanding of estrogen's function in the male reproductive tract is limited, and estrogen receptor (ER) localization in the reproductive tract of the adult male rat has not been described. ...
In the male brown-Norway (BN) male rat, reproductive aging is associated with decreased LH-pulse amplitude and area
FSH testosterone pulsatile secretion
2009/2/17
The Brown-Norway (BN) rat has been proposed as a rodent model for the study of human male reproductive aging. As in man, reduction in serum or plasma testosterone (T) and both testicular (primary)...
Copulatory behavior and fertility in transgenic male mice expressing human placental growth hormone gene
Sexual behavior placental growth hormone variant
2009/2/17
Male transgenic (TG) mice overexpressing the human placental growth hormone (GH) variant gene (hGH-V) exhibit reproductive deficits in spite of normal testosterone levels and normal sperm counts. ...
Use of a rat cDNA probe specific for the Y chromosome to detect male-derived cells
Sty gene polymerase chain reaction
2009/2/17
A cDNA probe that exhibits specificity for the rat Y chromosome was generated by using a set of primers specific to the murine Sry gene, the sex-determining region of the Y chromosome. A 459-base pa...
Decreased spermatogenesis as the result of an induced autoimmune reaction directed against the gonadotropin receptors in male rats
Spermatogenesis testis FSHR LHR sperm number autoimmune antireceptor antibody fertility
2009/2/17
The presence of luteinizing hormone (LH) and testosterone is considered critical for the maintenance of spermatogenesis in the rat. However, the role and importance of follicle-stimulating hormone...
The number and magnitude of studies involving testosterone-supplementation therapy in older men are limited. In addition, many studies to date have not been blinded or controlled, were reported in...
The relation between reactive oxygen species and cytokines in andrological patients with or without male accessory gland infection
IL-ia lL-6 IL-8 HGF spermatozoa male infertility
2009/2/17
The presence of various cytokines, namely hepatocyte growth factor (HGF), interleukin-1 receptor antagonist (IL-1 RA), and interleukins (IL-1 alpha, IL-6, and IL-8), as well as the production of rea...
P450 aromatase messenger ribonucleic acid expression in male rat germ cells: detection by reverse transcription-polymerase chain reaction amplification
Germ cells spermatids P450 aromatase estrogen
2009/2/17
We have previously demonstrated that cytochrome P450 aromatase (P450arom) protein, an estrogen-synthesizing enzyme, is present and active in germ cells of the adult mouse testis. To establish that P...
Catalase mRNA expression in the male rat reproductive tract
Catalase mRNA expression male rat
2009/2/16
Reactive oxygen species (ROS) have been shown to impair sperm function. The actions of ROS are reduced by antioxidant enzymes, including catalase. Although catalase-like activity has been demonstrated...
Oxidative stress and male infertility
Seminal plasma reactive oxygen species antioxidants infertility
2009/2/16
We have studied the activity of substances (superoxide dismutase [SOD], catalase [Cat], malonaldehyde, xanthine oxidase [XO], nitric oxide [NOx]) participating in oxidative stress. Seminal plasma sa...
Morphometric study of the gubernaculum in male estrogen receptor mutant mice
ERKO estrogen estrogen receptor cremaster processus vaginalis testis gubemaculum
2009/2/16
To determine role of estrogen receptors in testicular descent, a morphometric study of the testis and structures derived from the gubernaculum was made in sexually mature male mice having an estro...
Role of oxidative stress and antioxidants in male infertility
oxidative stress antioxidants male infertility
2009/2/13
Oxygen toxicity is an inherent challenge to aerobic life, including spermatozoa, the cells responsible for propagation of the species. How this toxicity affects the spermatozoan in its interactions wi...