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Controlled Release of Simvastatin Acid Using Cyclodextrin Inclusion System
Simvastatin acid Cyclodextrin derivative Controlled drug release
2009/9/14
Simvastatin acid (SVA) has been reported to stimulate bone formation by increasing expression of BMP-2 in osteoblasts. Due to their multi-functional characteristics and bioadaptability, cyclodextrins ...
Compressive Strength,Surface Roughness,Fluoride Release and Recharge of Four New Fluoride-releasing Fissure Sealants
Fissure sealants Fluoride release Physical properties
2009/9/14
The aim of this study was to investigate the compressive strength and surface roughness of two glass ionomer cements and two resin-based fissure sealants before and after fluoride release and recharge...
Corrosion-related Changes on Ti-based Orthodontic Brackets in Acetic NaF Solutions: Surface Morphology, Microhardness, and Element Release
Corrosion Bracket NaF solution
2009/9/11
This study sought to investigate the effects of acetic NaF solutions on titanium and Ti alloy brackets. To this end, two different brackets were immersed in various NaF-containing solutions for three ...
Fluoride release and recharge characteristics of denture base resins containing surface pre-reacted glass-ionomer filler
Fluoride releasing and recharging Denture base resin Surface pre-reacted glass-ionomer filler
2009/9/11
The flexural strength, flexural modulus, and the amount of fluoride released from four experimental denture base resins containing 5, 10, 20 and 30 wt% surface pre-reacted glass-ionomer (S-PRG) filler...
Hydrostatic pressure reduces synaptic efficiency by inhibiting transmitter release
drug pressure transmitter release
2009/7/16
The amplitude of post-synaptic potentials at an identified synapse in the Aplysia central nervous system can be modulated by the application of hydrostatic pressure. Postsynaptically controlled functi...
Recent studies have documented a marked inhibition of renal prostaglandin E2 excretion during hyperbaric oxygenation (HBO) in the conscious dog. Numerous other studies have shown that pharmacological ...
Effects of high pressure on the release of excitatory amino acids by brain synaptosomes
decompression neurological
2009/7/14
Excitatory amino acid antagonists have been shown to protect against the hyperexcitability associated with exposure to high pressure. This suggests that these excitatory neurotransmitter substances ma...
Pressure suppresses serotonin release by guinea pig striatal synaptosomes
animal guinea pig serotonin striatal synaptosomes high pressure nervous syndrome
2009/7/10
Exposure to high pressure produces neurologic changes in humans which manifest as tremor, EEG changes, and convulsions. Since previous studies have implicated the involvement of the serotoninergic sys...
Release of dopamine from striatal synaptosomes:high pressure effects
animal Guinea pig neurological high pressure neurologic syndrome
2009/7/10
Adverse neurological manifestations of exposure to high hydrostatic pressure include tremor and convulsions, suggesting an alteration in synaptic transmission, particularly with inhibitory pathways. B...
Rat brain catecholamine release at 1,10,20,and 100 ATA heliox,nitrox,and trimix
helium heliox nitrogen narcosis animal rat nitrox chamber catecholamine
2009/7/10
The pattern of neurotransmitter release in the rat caudate and hypothalamus was studied following exposure to pressure in combination with various gas mixtures. The caudate was selected for its contro...
Hyperbaric He but not N2 augments Ca2+-dependent dopamine release from rat striatum
animal rat high pressure neurologic syndrome
2009/7/9
Endogenous dopamine (DA) and 3,4-dihydroxyphenylacetic acid (DOPAC) were measured by high performance liquid chromatography with electrochemical detection in perfusate from continuously superfused rat...
Effect of pressure on the release of endogenous dopamine from rat striatum and the role of sodium-calcium exchange
model animal rat High Pressure Neurological Syndrome
2009/7/8
Exposure to environmental pressures in excess of 20 atm abs can precipitate a hyperexcitability state known as high pressure neurologic syndrome (HPNS). Little is known about the underlying neurochemi...
Biomedical Engineers Demonstrate Long-Sought After Capability for Entrapment and Release of Bioactive Agents（图）
Biomedical Engineers Long-Sought Entrapment Bioactive Agents
2009/7/20
Synthetic biomaterials hold the promise for engineering structures that enable controlled release of therapeutic drugs to targeted cells and organs and even cells for use in cell therapy and regenerat...
Significance of Cardiac Troponin T Release in Detecting Minor Myocardial Injury After Percutaneous Transluminal Coronary Angioplasty
Troponin T percutaneous transluminal coronary angioplasty
2009/6/30
Cardiac Troponin T (TnT) is a regulatory contractile protein not normally found in blood. Its detection in the circulation has been shown to be a sensitive and specific marker for myocardial cell dama...
Preparation of PHBV Foams and Investigation of Their Potential For Drug Release
Controlled Release Poly(hydroxybutyrate-co-hydroxyvalerate)-PHBV Polymer foams Tetracycline
2009/6/30
Polymeric foams seem to have potential for use in many research areas such as cell seeding and macromolecule or drug loading. Three factors were studied to evaluate the efficiency of foams as drug car...