搜索结果: 16-20 共查到“医学 SLE”相关记录20条 . 查询时间(0.052 秒)
摘要 从活动期SLE患者血清DNA/抗-DNA免疫复合物中分离DNA,用电镜观察结果表明:这些DNA是很不均质的双链片段。它们的分子量范围很宽,镜下可见的最小片段长553A(约150bp),最大片段长10431A(约2800bp),多数DNA片段长约200—400bp,与正常对照相比较有明显区别。另外,还观察到具有单链末端的双链DNA片段。
Isolated Hematuria in SLE Patients and its Association with Proteinuria, Uri-nary Cast and SLE Disease Activity
Isolated hematuria systemic lupus erythematosus SLE disease activity
2009/12/16
Isolated hematuria and its association with proteinuria, and urinary cast and systemic lupus erythematosus (SLE) disease activity, and decision for renal biopsy is a dilemma for physician in SLE patie...
系统性红斑狼疮(SLE)的表遗传学发病机制研究进展
系统性红斑狼疮 表遗传 DNA甲基化
2007/11/5
摘要 表遗传学是研究DNA序列没有发生改变的情况下基因表达的遗传变化。研究表明DNA甲基化异常可能与系统性红斑狼疮(systemic lupus erythematosus, SLE)发病有关。DNA调节序列的低甲基化与B和T淋巴细胞的激活与分化有关。SLE患者血浆中低甲基化基因组DNA片段,可能模仿了微生物DNA,诱导了抗dsDNA抗体的生物合成。HERV序列、外源性逆转录病毒和核抗原显示出极度...
Lupus Headaches in 55 Childhood-Onsets SLE
Lupus Headache Antiphospholipid antibody Antinuclear Antibodies
2010/4/6
Objective: Although headache is a common complaint among patients with lupus, no universally accepted explanation was available until the International Headaches Society adopted Lupus headache as a No...
A SURVEY OF ANTIBODIES FOR THE EXTRACTABLE NUCLEAR ANTIGENS AND THEIR ROLE IN THE CLINICAL DIAGNOSIS AND PROGNOSIS OF SLE
ANTIGENS THEIR ROLE CLINICAL DIAGNOSIS PROGNOSIS OF SLE
2010/5/7
Fifty-seven patients suffering from systemic lupus erythematosus with different clinical features were studied from various aspects of immunological abnormalities, including anti-nuclear antibodies; a...