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Omenn syndrome (OS) is a form of severe combined immunodeficiency (SCID) characterized by erythrodermia, hepatosplenomegaly, lymphadenopathy, and alopecia. In patients with OS, B cells are mostly abse...
Asthma therapy including inhaled corticosteroids (ICS) has been shown to be effective in many parts of the world, but its use is still limited in Japan. A 6-week, randomized, placebo-controlled, clini...
Pollinosis caused by Cryptomeria japonica is a very serious health problem in Japan. To clarify the relationship between C. japonica pollen emissions before the main pollen dispersal season and dorman...
To analyze the prevalence and severity of asthma, rhinitis and eczema in children living in different countries, the International Study of Asthma and Allergies in Childhood (ISAAC) was developed. The...
If China follows the same path as Japan, that is, proceeds with conversion from coal to oil as its primary energy source, the popularization of motor vehicles and chemical contamination of food, housi...
There is a major problem from asthma in Japan due to its high prevalence, morbidity, economic cost and mortality. The striking feature of the time trends in asthma mortality in Japan is the two epidem...
The prevalence of asthma has been increasing in Japan, like in other parts of the world. Asthma management guidelines were developed in Japan in 1993 and 1998. These guidelines have been shown to cont...
Based on sufficient consideration of the problems specifically related to elderly asthmatic patients, adequate education and careful management of asthma in this group are required, and the accumulati...
Background: Allergens that cause food allergy vary considerably according to race, environment, dietary habits and age. However, data on the actual situation of food allergy in young adult students ar...
In analyses of family histories, the odds ratios (OR) of children who have a family history with no symptoms were significantly lower by risk factor-based analyses compared with those children with a ...
The first successful lung transplantation (LTx) was performed in 1983. Since then, more than 10000 LTx have been performed in the world, with approximately 1000 new cases each year in recent years. Lu...
Recent asthma deaths were examined from yearly reports of the Ministry of Health, Labor and Welfare of Japan and from reports published by the Japan Asthma Death Investigation Committee on 811 deaths ...
These results indicate that anti-inflammatory agents, including inhaled corticosteroids and leukotriene receptor antagonists, contributed to improved asthma control, whereas oral theophylline is chara...
The relationships between the fungal conditions in the indoor environment found around the Kanto District and parameters such as the season, area in the house and indoor environment were analyzed. Acc...
We now live in a world where the threat of emerging and re-emerging infectious diseases crosses continental and national borders. In recognition of this trend the world realizes the importance of nurt...

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