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In this study, changes in the number of androgen binding sites that occur in cytosols of epididymis, vas deferens and seminal vesicle of mice from 10 to 90 days of age are described. Specific satura...
Chronic renal insufficiency was induced in young adult male rats by a 2-step 5/6 nephrectomy. Four weeks after surgery the rats were anesthetized with ketamine and injected with saline or 1, 5, 10...
The testosterone dose-dependency of several mating and nonmating behaviors was examined in the male rat, chemically castrated with a GnRH antagonist analog. Graded doses of testosterone enanthate ...
To understand the involvement of polyamines in testicular maturation and spermatogenesis, the activity of two enzymes involved in the polyamine synthetic pathway, L-ornithine decarboxylase (ODC) a...
The review has four objectives. The first objective is to summarize our studies of gene mutations that induce infertility in male mice. The second objective is to stress the power of mouse genetics ...
Cocaine hydrochloride (30, 15, or 0 mg/kg) was administered daily subcutaneously to male rats for a minimum of 72 days. Animals receiving the 15-mg/kg and 0-mg/kg doses were pair-fed with animals re...
This study determined the quantitative and qualitative histopathologic effects of a single oral dose of 1,3-dinitrobenzene (48 mg/kg) on the rat testis from 1 to 175 days postexposure. The testis was ...
Groups of eight adult male rats were given a single oral dose of 0 or 48 mg/kg of 1,3-dinitrobenzene and sacrificed at 1, 2, 4, 8, 16, 24, 32, 72, and 175 days posttreatment. The groups killed at 17...
The second generation descended from rats treated either with cyclophosphamide alone or with both cyclophosphamide and vinblastine were investigated. As in the first generation, the offspring were...
Four experiments were designed to investigate the influence of photoperiod and other environmental factors on androgen production and reproductive maturation in deer mice. Male prairie deer mice (Pe...
In this study, the frequency and titers of serum antibodies to Chlamydia trachomatis in fertile and subfertile subjects and possible correlations between a positive serology and the values of conven...
The development of the reproductive response to short photoperiod in golden hamsters was examined by monitoring testis size in hamsters that were either: raised on 14L:10D from birth; raised on 6L:1...
The effect of water restriction on the pituitary-gonadal axis has been studied in adult male rats. Water restriction did not modify FSH, LH and testosterone levels. However, both LH and testosterone...
The spermatogenesis and the offspring of male rats treated either with cyclophosphamide alone, or with both cyclophosphamide and vinblastine were investigated. The offspring were evaluated for the...
A study was conducted to explore the hypothesis that reduced caloric intake increases the negative feedback efficacy of testosterone on gonadotropin secretion. Daily subcutaneous injections of testost...

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