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Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat
cyclooxygenase-2 COX-2 COX-1 prostaglandin E2 neuroinflammation blood-brain barrier ischemia stroke matrix metalloproteinase MMP-3 MMP-9 gelatinase B stromelysin-1 oxidative stress indomethacin cyclooxygenase-1 glutathione free radicals MRI
2015/7/29
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-alp...
Cyclooxygenase inhibition in ischemic brain injury.
cyclooxygenase-2 ischemia stroke cerebral ischemia neuroinflammation excitotoxicity
2015/7/28
Neuroinflammation is one of the key pathological events involved in the progression of brain damage caused by cerebral ischemia. Metabolism of arachidonic acid through cyclooxygenase (COX) enzymes is ...
Crosstalk Between Brain-Derived Neurotrophic Factor And N-Methyl-D-Aspartate Receptor Signaling In Neurons
NMDA receptor BDNF neurotrophins
2015/7/28
Glutamate is the major excitatory neurotransmitter in brain exerting prosurvival effect on neurons via N-methyl-D-aspartate receptor (NMDAR) signaling under physiological conditions. However in pathol...
Meningeal Hemangiopericytoma of Brain: Role of Radiation Therapy
Brain tumor Radiotherapy Hemangiopericytoma
2015/7/10
Hemangiopericytoma is an uncommon vascular tumour. Complete surgical resection is treatment of choice. However, late local recurrences and distant extraneural metastases ranging from 12% to 57% are re...
Capitol Hill briefing on mysteries of the brain:Frontiers in neuroscience
Capitol Hill briefing mysteries of the brain neuroscience
2015/7/13
The most mysterious biological organ on Earth is lodged right between your ears: your brain.Members of the news media are invited to join the National Science Foundation, the Society for Neurosci...
Co-Variations among Cognition, Cerebellar Disorders and Cortical Areas With Regional Glucose-Metabolic Activities in a Homogeneous Sample with Uner Tan Syndrome: Holistic Functioning of the Human Brain
Uner Tan syndrome ataxia intelligence neural network holistic brain
2015/6/10
Patients with Uner Tan syndrome (UTS) exhibit habitual quadrupedal locomotion (QL), intellectual disability, dysarthric speech and truncal ataxia. Examination of cognitive ability in this syndrome has...
A new video series released today takes viewers on a journey to unlock the mysteries of the brain and better understand how this complex organ functions. Produced by NBC Learn, the educational ar...
Brain's reaction to certain words could replace passwords
Brain's reaction certain words replace passwords
2015/6/18
You might not need to remember those complicated e-mail and bank account passwords for much longer. According to a new study, the way your brain responds to certain words could be used to replace pass...
Eye-Movement Brain Potentials and Family History of Alcoholism: Alcoholism, brain potentials, saccades, antisaccades
brain potentials saccades antisaccade
2015/5/26
This Master of Science thesis, eye movements brain potentials and family history of alcoholism, has been completed at the Neural Systems Laboratory of Dr. Sean O’Connor. I am greatly indebted for the ...
The Effects of Aerobic Exercise Intensity and Duration on Levels of Brain-Derived Neurotrophic Factor in Healthy Men
Aerobic brain-derived neurotrophic factor (BDNF) exercise human neurotrophins
2015/5/18
This study examined the combined effects of aerobic exercise intensity and duration on serum brain-derived neurotrophic factor (sBDNF) levels in healthy human adult males aged 18-25 years. Forty five ...
How noise changes the way the brain gets information
noise changes the way brain gets information
2015/5/25
That’s one major finding of a study out today in the Early Edition of the Proceedings of the National Academy of Sciences.Expose the cells to loud sounds for a prolonged period of time, and they alter...
Brain tumours: Successes and challenges on the other side of the blood-brain barrier
Brain tumours the blood-brain barrier cancers
2015/4/21
Tumours of the central nervous system encompass a large variety of cancers, ranging from slow-growing to rapidly progressive. Although comparatively rare in adults, central nervous system malignancies...
Drugs that target insulin pathways to slow or stop the growth of brain tumors are going in the right direction but appear to be on the wrong track, according to new research at Rice University.Through...
Exertion Testing in Youth with Mild Traumatic Brain Injury/Concussion
RETURN TO PLAY HEAD INJURY BRAIN CONCUSSION POSTCONCUSSION SYNDROME CHILDREN ADOLESCENTS
2017/4/20
Purpose: The decision regarding return to activity (RTA) after mild traumatic brain injuries/concussion is one of the most difficult and controversial areas in concussion management, particularly for ...
Physical Activity, Fitness, Glucose Homeostasis, and Brain Morphology in Twins
EXERCISE FITNESS BODY COMPOSITION GRAY MATTER VOLUME GLUCOSE
2017/4/14
Purpose: The main aim of the present study (FITFATTWIN) was to investigate how physical activity level is associated with body composition, glucose homeostasis, and brain morphology in young adult mal...