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Previous reports concerning isolated follicle stimulating hormone (FSH) deficiency and its possible pathogenesis have been conflicting. Both "normal" and "abnormal" FSH response to luteinizing hormone...
Steroid regulation of pituitary LH and FSH secretion in the male may be mediated via the direct action of testosterone, or via the conversion of testosterone to either dihydrotestosterone (DHT) or e...
The goal of this investigation was to assess whether or not gonadotropin therapy enhanced the degree of virilization and psychosexual behavior of men with hypogonadotropic hypopituitarism. Pre- and ...
A highly potent agonist of LHRH, [6-D-(2-naphthyl)-alanine]-LHRH, was administered chronically for 12 weeks to adult male rats by repetitive implantation of pellets, and its effects upon mating, fer...
(+)-Gossypol was isolated from the bark of Thespesia populnea and tested for its ability to inhibit the fertility of male hamsters. Male hamsters of proven fertility were treated orally for 54 days ...
The effects of the male antifertility agents alpha-chlorohydrin, 5-thio-D-glucose, and 6-chloro-6-deoxy-D-glucose on sugar transport (3H-3-O-methyl-D-glucose and 3H-2-deoxy-D-glucose) across the r...
To determine whether estrogens may play a role in the decline in Leydig cell function in aged rats, plasma levels of testosterone, estradiol, and estrone; intratesticular concentrations of testoster...
Estradiol partially maintained the weights of the dorsolateral prostate and seminal vesicles in castrated adult male rats. One group of animals received subcutaneous injections of estradiol (0.01 ...
The effect of acute and chronic administration of ethanol on prolactin secretion in male rats was investigated under basal conditions and after the administration of sulpiride. The effect of ethan...
Studies were conducted to characterize the responses of the hypothalamic-pituitary-testicular axis to systemic injection of estradiol benzoate (EB) in the rat. Feedback effects of estrogens on the...
Five groups of immature (30-day-old) intact male rats were injected daily for ten days with different doses of ovine prolactin (5, 10, 25, 50, or 500 µg per rat per day). At the end of the t...
Exposure of immature male rats to 5% (w/v) ethanol as the sole drinking fluid from weaning age (21 days of age) resulted in a delay in balanopreputial separation (41.3 ± 1.4 days versus 37.6 ± 2.0 d...
To characterize the effects of testosterone (T) pretreatment on the response of pituitary LH secretion to exogenous gonadotropin-releasing hormone (GnRH), intact male dogs were injected subcutaneo...
A 51-year-old man with previously diagnosed bilateral anorchia was shown by endocrine investigation of his hypophyseal-gonadal axis to have functioning testicular tissue. The implications of endocri...
The development of male contraceptive drugs is of great scientific importance for andrologists as well as being of vital world interest. The American Society of Andrology, therefore, welcomed the op...

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