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Effects of Gossypol on the Reproductive System of Male Rats
gossypol fertility male rat testosterone LH FSH sperm morphology Leydig cell
2009/2/19
Gossypol acetic acid administered orally at 30 mg/kg body weight/day for five weeks inhibited the fertility of male rats without an apparent loss of libido. Sperm in the ejaculate were rendered immo...
Some Aspects of Pituitary Function in the Male Diabetic
pituitary function diabetes gonadotropin releasing hormone (GnRH) thyrotropin releasing hormone (TRH) growth hormone
2009/2/19
In order to elucidate the hypothalamic-pituitary function in diabetes, the pituitary responsiveness of LH, FSH, prolactin (PRL), and growth hormone (GH) to a thyrotropin releasing hormone (TRH, 200 ...
In Vivo and In Vitro Investigation of the Extrapituitary Antireproductive Effects of a Potent LHRH Agonist in Immature and Adult Male Rats
LHRH agonist extrapituitary reproductive effects age-dependency hypophysectomy
2009/2/19
Co-incubation with a potent LHRH agonist, D-Ala6-Des-Gly10-Pro9-NHEt-LHRH (Wy-18,481), did not affect testosterone or progesterone production by adult intact rat testes in vitro. Prior administrat...
Interactive Effects of Ethanol and 9-Tetrahydrocannabinol on Endocrine Functions in Male Mice
ethanol 9-tetrahydrocannabinol testes in vitro testosterone production plasma testosterone
2009/2/19
Exposure during sexual maturation to alcohol (ETOH) plus 9-tetrahydrocannabinol (THC) significantly decreased the weights of adrenals, kidneys, testes, and emptied seminal vesicles ten days after ce...
Prolactin Stimulation of Testicular Steroid Biosynthesis in the Male Rat
prolactin LHRH 17-hydroxylase desensitization steroidogenesis LH receptor prolactin receptor
2009/2/19
The effect of prolactin on testicular steroidogenesis was studied in intact adult male rats and in animals treated for 12 days with the LHRH-agonist [D-Ala6, des-Gly-NH210]LHRH ethylamide (LHRH-agon...
The Suitability of Silver and Platinum Coils as Intravasal Devices for Male Fertility Control in Rats
male fertility control intravasal devices surgical methods
2009/2/18
In 91 male rats, silver or platinum coils were implanted into the vasa deferentia with the hope of developing a simple and reversible method for male fertility control. The insertion of the coil by ...
Antifertility Effects of LHRH Agonists in the Male
LHRH agonists LH receptor prolactin receptor LHRH receptor desensitization spermatogenesis
2009/2/18
Acute or chronic treatment of adult male rats with LHRH or its agonists leads to a loss of testicular LH and prolactin receptors accompanied by decreased testis, seminal vesicle, and ventral prost...
Nuclear Uptake and Retention of Androgen by the Accessory Organs in the Male Golden Hamster
androgens 3H-dihydrotestosterone autoradiography male accessory organs
2009/2/18
The nuclear uptake and retention of 3H-dihydrotestosterone (3H-DHT) were studied in the reproductive organs of the male hamster by autoradiography. Castrated adult male hamsters were injected with...
Testosterone Regulation of Follicle-stimulating Hormone Secretion in the Male Dog
testosterone FSH polydimethylsiloxane
2009/2/18
Studies were carried out to determine the effect of various numbers of testosterone-filled polydimethylsiloxane (PDS)capsules on plasma concentrations of testosterone and FSH in acutely orchidectomi...
Diabetes mellitus in man is frequently associated with sexual dysfunction. It is now generally agreed that retrograde ejaculation and impotence in diabetic men are caused in the majority of cases by...
Evaluation of oxidative DNA damage in human sperm and its association with male infertility
8-Hydroxydeoxyguanosine spermatozoa infertility
2009/2/18
Recently, there is increasing evidence suggesting that oxidative sperm DNA damage is closely associated with impaired sperm function and male infertility. 8-Hydroxydeoxyguanosine (8-OHdG) is consi...
The development of male reproductive organ abnormalities after neonatal exposure to tamoxifen is genetically determined
Neonate mice strains testicular infarction epididymitis
2009/2/18
Responses of the male reproductive organs to neonatal exposures of tamoxifen (Tx) were examined in seven different strains of mice (A/J, AKR/J, BALB/cAnN, C3H/HeJ, C57BL/6J, DBA/ 2J, and FVB/N). Mal...
Temporal relation between leptin and various indices of sexual maturation in the male rat
Puberty adipose tissue testosterone gonadotropins
2009/2/18
Recent studies in humans and rhesus monkeys have suggested the possibility that the adipose tissue hormone leptin has a stimulatory and/or permissive effect on the onset of puberty in the male. We...
Evidence that in a physiological setting Sertoli cell number is the major determinant of circulating concentrations of inhibin B in the adult male rhesus monkey（Macaca mulatta）
Sertoli cell number circulating concentrations inhibin B adult male rhesus monkey
2009/2/18
The relationship between changes in Sertoli cell number and function and changes in circulating inhibin B concentrations was investigated following unilateral orchidectomy (UO) in the adult rhesus...
Inhibin B levels in plasma of the male rat from birth to adulthood：effect of experimental manipulation of Sertoli cell number
Inhibin B levels male rat experimental manipulation Sertoli cell number
2009/2/18
Sertoli cells undergo important changes in their number and function at different ages in the rat and may be the primary source of circulating inhibin B. The aims of this study were 1) to establis...