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Genetic defects in downregulation of IgE production and a new genetic classification of atopy
atopy IgE production downregulation interferon-γ interleukin-12 receptor β2 interleukin-18 receptor α
2010/11/22
Atopic disorders, such as asthma, eczema and rhinitis, develop due to the interactions between genetic and environmental factors. Atopy is characterized by enhanced IgE responses to environmental anti...